Cannabinoids and the expanded endocannabinoid system in neurological disorders
L Cristino, T Bisogno, V Di Marzo - Nature Reviews Neurology, 2020 - nature.com
Anecdotal evidence that cannabis preparations have medical benefits together with the
discovery of the psychotropic plant cannabinoid Δ9-tetrahydrocannabinol (THC) initiated …
discovery of the psychotropic plant cannabinoid Δ9-tetrahydrocannabinol (THC) initiated …
Cannabinoids as anticancer drugs: current status of preclinical research
B Hinz, R Ramer - British journal of cancer, 2022 - nature.com
Drugs that target the endocannabinoid system are of interest as pharmacological options to
combat cancer and to improve the life quality of cancer patients. From this perspective …
combat cancer and to improve the life quality of cancer patients. From this perspective …
Cannabidiol: State of the art and new challenges for therapeutic applications
Over the past years, several lines of evidence support a therapeutic potential of Cannabis
derivatives and in particular phytocannabinoids. Δ 9-THC and cannabidiol (CBD) are the …
derivatives and in particular phytocannabinoids. Δ 9-THC and cannabidiol (CBD) are the …
[HTML][HTML] Terpenes in Cannabis sativa–From plant genome to humans
JK Booth, J Bohlmann - Plant Science, 2019 - Elsevier
Cannabis sativa (cannabis) produces a resin that is valued for its psychoactive and
medicinal properties. Despite being the foundation of a multi-billion dollar global industry …
medicinal properties. Despite being the foundation of a multi-billion dollar global industry …
From phytocannabinoids to cannabinoid receptors and endocannabinoids: pleiotropic physiological and pathological roles through complex pharmacology
A Ligresti, L De Petrocellis… - Physiological …, 2016 - journals.physiology.org
Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …
[HTML][HTML] Anticancer mechanisms of cannabinoids
In addition to the well-known palliative effects of cannabinoids on some cancer-associated
symptoms, a large body of evidence shows that these molecules can decrease tumour …
symptoms, a large body of evidence shows that these molecules can decrease tumour …
The endocannabinoid system as an emerging target of pharmacotherapy
The recent identification of cannabinoid receptors and their endogenous lipid ligands has
triggered an exponential growth of studies exploring the endocannabinoid system and its …
triggered an exponential growth of studies exploring the endocannabinoid system and its …
Towards the use of cannabinoids as antitumour agents
Various reports have shown that cannabinoids (the active components of marijuana and
their derivatives) can reduce tumour growth and progression in animal models of cancer, in …
their derivatives) can reduce tumour growth and progression in animal models of cancer, in …
The endocannabinoid system: A target for cancer treatment
In recent years, the endocannabinoid system has received great interest as a potential
therapeutic target in numerous pathological conditions. Cannabinoids have shown an …
therapeutic target in numerous pathological conditions. Cannabinoids have shown an …
Programming of neural cells by (endo) cannabinoids: from physiological rules to emerging therapies
M Maccarrone, M Guzmán, K Mackie… - Nature Reviews …, 2014 - nature.com
Among the many signalling lipids, endocannabinoids are increasingly recognized for their
important roles in neuronal and glial development. Recent experimental evidence suggests …
important roles in neuronal and glial development. Recent experimental evidence suggests …