DNA nanotechnology-empowered nanoscopic imaging of biomolecules

F Li, J Li, B Dong, F Wang, C Fan, X Zuo - Chemical Society Reviews, 2021 - pubs.rsc.org
Advances in bioimaging technologies have led to unprecedented findings of novel
biological processes at the nanoscale. However, there remains an ever-lasting demand for …

Data storage based on DNA

Y Hao, Q Li, C Fan, F Wang - Small Structures, 2021 - Wiley Online Library
Recent years have witnessed the exponential growth of information, calling for the
development of new storage media. DNA provides an attractive alternative for data storage …

Programming dissipation systems by DNA timer for temporally regulating enzyme catalysis and nanostructure assembly

Z Qin, Y Liu, L Zhang, J Liu, X Su - ACS nano, 2022 - ACS Publications
Live cells precisely control their temporal pattern in energy dissipative processes such as
catalysis and assembly. Here, we demonstrate a DNA-based artificial dissipative …

Encoding fluorescence anisotropic barcodes with DNA frameworks

Q Huang, B Chen, J Shen, L Liu, J Li, J Shi… - Journal of the …, 2021 - ACS Publications
Fluorescence anisotropy (FA) holds great potential for multiplexed analysis and imaging of
biomolecules since it can effectively discriminate fluorophores with overlapping emission …

Determining sequence-dependent DNA oligonucleotide hybridization and dehybridization mechanisms using coarse-grained molecular simulation, markov state …

MS Jones, B Ashwood, A Tokmakoff… - Journal of the …, 2021 - ACS Publications
A robust understanding of the sequence-dependent thermodynamics of DNA hybridization
has enabled rapid advances in DNA nanotechnology. A fundamental understanding of the …

Recent applications of FRET-based multiplexed techniques

A Kaur, S Dhakal - TrAC Trends in Analytical Chemistry, 2020 - Elsevier
Fluorescence resonance energy transfer (FRET) has become a powerful tool for visualizing
molecular interactions, single-molecule conformational dynamics, binding, and other …

High-speed super-resolution imaging using protein-assisted DNA-PAINT

M Filius, TJ Cui, AN Ananth, MW Docter, JW Hegge… - Nano …, 2020 - ACS Publications
Super-resolution imaging allows for the visualization of cellular structures on a nanoscale
level. DNA-PAINT (DNA point accumulation in nanoscale topology) is a super-resolution …

Using strand displacing polymerase to program chemical reaction networks

S Shah, J Wee, T Song, L Ceze, K Strauss… - Journal of the …, 2020 - ACS Publications
Chemical reaction networks (CRNs) provide a powerful abstraction to formally represent
complex biochemical processes. DNA provides a promising substrate to implement the …

Single-molecule analysis of nucleic acid biomarkers–A review

T Gilboa, PM Garden, L Cohen - Analytica chimica acta, 2020 - Elsevier
Nucleic acids are important biomarkers for disease detection, monitoring, and treatment.
Advances in technologies for nucleic acid analysis have enabled discovery and clinical …

DNA-templated timer probes for multiplexed sensing

Y Deng, L Ma, Q Han, C Yu, A Johnson-Buck, X Su - Nano Letters, 2020 - ACS Publications
Simultaneous analysis based on encoded fluorophores suffers from potential crosstalk
between fluorophores and the limited number of colors that can be practically resolved …