Diversity in chemical structures and biological properties of plant alkaloids
S Bhambhani, KR Kondhare, AP Giri - Molecules, 2021 - mdpi.com
Phytochemicals belonging to the group of alkaloids are signature specialized metabolites
endowed with countless biological activities. Plants are armored with these naturally …
endowed with countless biological activities. Plants are armored with these naturally …
Tropane alkaloids: chemistry, pharmacology, biosynthesis and production
KL Kohnen-Johannsen, O Kayser - Molecules, 2019 - mdpi.com
Tropane alkaloids (TA) are valuable secondary plant metabolites which are mostly found in
high concentrations in the Solanaceae and Erythroxylaceae families. The TAs, which are …
high concentrations in the Solanaceae and Erythroxylaceae families. The TAs, which are …
Biosynthesis of medicinal tropane alkaloids in yeast
P Srinivasan, CD Smolke - Nature, 2020 - nature.com
Tropane alkaloids from nightshade plants are neurotransmitter inhibitors that are used for
treating neuromuscular disorders and are classified as essential medicines by the World …
treating neuromuscular disorders and are classified as essential medicines by the World …
Revealing evolution of tropane alkaloid biosynthesis by analyzing two genomes in the Solanaceae family
Tropane alkaloids (TAs) are widely distributed in the Solanaceae, while some important
medicinal tropane alkaloids (mTAs), such as hyoscyamine and scopolamine, are restricted …
medicinal tropane alkaloids (mTAs), such as hyoscyamine and scopolamine, are restricted …
Alkaloid biosynthesis: metabolism and trafficking
J Ziegler, PJ Facchini - Annu. Rev. Plant Biol., 2008 - annualreviews.org
Alkaloids represent a highly diverse group of compounds that are related only by the
occurrence of a nitrogen atom in a heterocyclic ring. Plants are estimated to produce …
occurrence of a nitrogen atom in a heterocyclic ring. Plants are estimated to produce …
Mining the biodiversity of plants: a revolution in the making
Only a small fraction of the immense diversity of plant metabolism has been explored for the
production of new medicines and other products important to human well-being. The …
production of new medicines and other products important to human well-being. The …
Expansion of chemical space for natural products by uncommon P450 reactions
X Zhang, S Li - Natural product reports, 2017 - pubs.rsc.org
Covering: 2000 to 2017 Cytochrome P450 enzymes (P450s) are the most versatile
biocatalysts in nature. The catalytic competence of these extraordinary hemoproteins is …
biocatalysts in nature. The catalytic competence of these extraordinary hemoproteins is …
RNA interference: promising approach to combat plant viruses
S Akbar, Y Wei, MQ Zhang - International Journal of Molecular Sciences, 2022 - mdpi.com
Plant viruses are devastating plant pathogens that severely affect crop yield and quality.
Plants have developed multiple lines of defense systems to combat viral infection. Gene …
Plants have developed multiple lines of defense systems to combat viral infection. Gene …
The molecular cloning of artemisinic aldehyde Δ11 (13) reductase and its role in glandular trichome-dependent biosynthesis of artemisinin in Artemisia annua
Y Zhang, KH Teoh, DW Reed, L Maes… - Journal of Biological …, 2008 - ASBMB
At some point during biosynthesis of the antimalarial artemisinin in glandular trichomes of
Artemisia annua, the Δ11 (13) double bond originating in amorpha-4, 11-diene is reduced …
Artemisia annua, the Δ11 (13) double bond originating in amorpha-4, 11-diene is reduced …
Plant cytochrome P450 plasticity and evolution
The superfamily of cytochrome P450 (CYP) enzymes plays key roles in plant evolution and
metabolic diversification. This review provides a status on the CYP landscape within green …
metabolic diversification. This review provides a status on the CYP landscape within green …