[HTML][HTML] Cryo-EM structure of the SARS-CoV-2 3a ion channel in lipid nanodiscs
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes the
coronavirus disease 2019 (COVID-19). SARS-CoV-2 encodes three putative ion channels …
coronavirus disease 2019 (COVID-19). SARS-CoV-2 encodes three putative ion channels …
[HTML][HTML] Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism
Thousands of outer-arm dyneins (OADs) are arrayed in the axoneme to drive a rhythmic
ciliary beat. Coordination among multiple OADs is essential for generating mechanical …
ciliary beat. Coordination among multiple OADs is essential for generating mechanical …
[HTML][HTML] M. mazei glutamine synthetase and glutamine synthetase-GlnK1 structures reveal enzyme regulation by oligomer modulation
MA Schumacher, R Salinas, BA Travis… - Nature …, 2023 - nature.com
Glutamine synthetases (GS) play central roles in cellular nitrogen assimilation. Although GS
active-site formation requires the oligomerization of just two GS subunits, all GS form large …
active-site formation requires the oligomerization of just two GS subunits, all GS form large …
[PDF][PDF] Cryo-EM structures of outer-arm dynein array bound to microtubule doublet reveal a mechanism for motor coordination
Thousands of outer-arm dyneins (OADs) are arrayed in the axoneme to drive a rhythmic
ciliary beat. Using electron microscopy, we determined the structure of OAD array bound to …
ciliary beat. Using electron microscopy, we determined the structure of OAD array bound to …
Structural mechanism for amino acid-dependent Rag GTPase switching by SLC38A9
The mechanistic target of rapamycin complex 1 (mTORC1) couples cell growth to nutrient,
energy and growth factor availability (–). mTORC1 is activated at the lysosomal membrane …
energy and growth factor availability (–). mTORC1 is activated at the lysosomal membrane …