Cell migration is an adaptive process that depends on and responds to physical and
molecular triggers. Moving cells sense and respond to tissue mechanics and induce …

The way in which a cell migrates is influenced by the physical properties of its surroundings,
in particular the properties of the extracellular matrix. How the physical aspects of the cell's …

Simple Summary The formation of new blood vessels from already existing ones is a
process of high clinical relevance, since it is of great importance for both physiological and …

Wound healing remains a challenging clinical problem and correct, efficient wound
management is essential. Much effort has been focused on wound care with an emphasis …

Bone marrow mesenchymal stem cells (MSCs) are a valuable cell source for tissue
engineering and regenerative medicine. Transforming growth factor β (TGF-β) can promote …

Mechanical forces influence different cell types in our bodies. Among the earliest forces
experienced in mammals is blood movement in the vascular system. Blood flow starts at the …

Cell migration results from stepwise mechanical and chemical interactions between cells
and their extracellular environment. Mechanistic principles that determine single-cell and …

Vascular endothelial cells (ECs) form a semiselective barrier for macromolecules and cell
elements regulated by dynamic interactions between cytoskeletal elements and cell …

Endothelial cells (ECs) line all blood vessel walls and are exposed to the mechanical forces
of blood flow which modulate their function and play a role in vascular regulation …

It has been well established that wall shear stress is an important determinant of endothelial
cell function and gene expression as well as of its structure. There is increasing evidence …