TGF-β signaling networks in the tumor microenvironment

MKK Chan, JYF Chung, PCT Tang, ASW Chan, JYY Ho… - Cancer letters, 2022 - Elsevier
Transforming growth factor-β (TGF-β) signaling shows important roles in both physiology
and pathology, especially in the progression of inflammatory diseases including cancer …

TGF-β signaling in metastatic colorectal cancer (mCRC): from underlying mechanism to potential applications in clinical development

X Li, Y Wu, T Tian - International journal of molecular sciences, 2022 - mdpi.com
Colorectal cancer (CRC) is a serious public health issue, and it has the leading incidence
and mortality among malignant tumors worldwide. CRC patients with metastasis in the liver …

[HTML][HTML] Aluminium bioaccumulation in colon cancer, impinging on epithelial-mesenchymal-transition and cell death

R Bonfiglio, R Sisto, S Casciardi, V Palumbo… - Science of The Total …, 2024 - Elsevier
We investigated the presence of aluminium (Al) in human colon cancer samples and its
potential association with biological processes involved in cancer progression, such as …

Gene/environment interaction in the susceptibility of Crohn's disease patients to aluminum

M Djouina, C Waxin, F Leprêtre, M Tardivel… - Science of The Total …, 2022 - Elsevier
Background & aim The key role of environmental factors in the pathogenesis of Inflammatory
Bowel Diseases (IBD) is recognized. Aluminum is suspected to be a risk factor for IBD …

Tebuconazole fungicide induces lipid accumulation and oxidative stress in HepG2 cells

HC Kwon, DH Kim, CH Jeong, YJ Kim, JH Han, SJ Lim… - Foods, 2021 - mdpi.com
Tebuconazole (TEB), a triazole fungicide, is frequently applied to agriculture for the increase
of food production. Although TEB causes liver toxicity, its effects on cellular lipid …

Contributing factors common to COVID‑19 and gastrointestinal cancer

RN Kostoff, MB Briggs, D Kanduc… - Oncology …, 2022 - spandidos-publications.com
The devastating complications of coronavirus disease 2019 (COVID‑19) result from the
dysfunctional immune response of an individual following the initial severe acute respiratory …

[HTML][HTML] Influence of Gelatin on Adhesion, Proliferation, and Adipogenic Differentiation of Adipose Tissue-Derived Stem Cells Cultured on Soy Protein–Agarose …

SJ Hong, DH Kim, JH Ryoo, SM Park, HC Kwon… - Foods, 2024 - mdpi.com
Scaffolds play a key role in cultured meat production by providing an optimal environment
for efficient cell attachment, growth, and development. This study investigated the effects of …

Celastrus orbiculatus extract inhibits the epithelial-mesenchymal transition process by transforming growth factor-β signaling pathway in gastric cancer

H Wang, Z Chu, S Ou, T Ni, X Dai… - Anti-Cancer Agents in …, 2022 - ingentaconnect.com
Background: Gastric cancer is the fifth most common tumor and has the third-highest
mortality rate among various malignant tumors, and the survival rate of patients is low …

[HTML][HTML] Evaluating the Diverse Anticancer Effects of Laos Kaempferia parviflora (Black Ginger) on Human Melanoma Cell Lines

GS Park, J Shin, S Hong, RK Saini, J Gopal, JW Oh - Medicina, 2024 - mdpi.com
Cancer has become a consistent concern globally and increasingly fatal. Malignant
melanoma is a rising concern, with its increased mortality. Kaempferia parviflora Wall. ex …

Cellular and molecular effects of fipronil in lipid metabolism of HepG2 and its possible connection to non‐alcoholic fatty liver disease

CC Pansa, LR Molica… - … of Biochemical and …, 2024 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is a global public health problem that affects more
than a quarter of the population. The development of this disease is correlated with …