Transcriptionally active chromatin is marked by tri-methylation of histone H3 at lysine 4
(H3K4me3) located after first exons and around transcription start sites. This epigenetic mark …

H2A. Z is a histone variant that provides specific structural and docking-side properties to the
nucleosome, resulting in diverse and specialised molecular and cellular functions. In this …

The human face is complex and multipartite, and characterization of its genetic architecture
remains challenging. Using a multivariate genome-wide association study meta-analysis of …

Deletion of the gene encoding the chromatin remodeler CHD1 is among the most common
alterations in prostate cancer (PCa); however, the tumor-suppressive functions of CHD1 and …

Chromatin is highly dynamic, undergoing continuous global changes in its structure and
type of histone and DNA modifications governed by processes such as transcription, repair …

Darolutamide is a novel androgen receptor (AR) antagonist with a distinct chemical structure
compared to other AR antagonists and currently in clinical Phase 3 trials for prostate cancer …

Facial morphology is highly variable, both within and among human populations, and a
sizable portion of this variation is attributable to genetics. Previous genome scans have …

Prostate cancer (PCa) is one of the most frequent tumor types in the male Western
population. Early‐stage PCa and late‐stage PCa are dependent on androgen signaling …

Objectives Long non‐coding RNA (lncRNA) MATN1‐AS1 is a newfound lncRNA that has
been rarely explored in cancers. Herein, we would like to investigate its role in glioma …

The analysis of contemporary genomic data typically operates on one-dimensional
phenotypic measurements (eg standing height). Here we report on a data-driven, family …