Emerging phagocytosis checkpoints in cancer immunotherapy

Y Liu, Y Wang, Y Yang, L Weng, Q Wu… - Signal transduction and …, 2023 - nature.com
Cancer immunotherapy, mainly including immune checkpoints-targeted therapy and the
adoptive transfer of engineered immune cells, has revolutionized the oncology landscape as …

Pre-and peri-implantation Zika virus infection impairs fetal development by targeting trophectoderm cells

L Tan, LA Lacko, T Zhou, D Tomoiaga… - Nature …, 2019 - nature.com
Zika virus (ZIKV) infection results in an increased risk of spontaneous abortion and poor
intrauterine growth although the underlying mechanisms remain undetermined. Little is …

Understanding the impact of ErbB activating events and signal transduction on antigen processing and presentation: MHC expression as a model

AE Kersh, M Sasaki, LA Cooper, HT Kissick… - Frontiers in …, 2016 - frontiersin.org
Advances in molecular pathology have changed the landscape of oncology. The ability to
interrogate tissue samples for oncogene amplification, driver mutations, and other molecular …

[HTML][HTML] MIIP accelerates epidermal growth factor receptor protein turnover and attenuates proliferation in non-small cell lung cancer

J Wen, J Fu, Y Ling, W Zhang - Oncotarget, 2016 - ncbi.nlm.nih.gov
The migration and invasion inhibitory protein (MIIP) has been discovered recently to have
inhibitory functions in cell proliferation and migration. Overexpression of MIIP reduced the …

Leveraging human–mouse studies to advance the genetics of hearing impairment in Africa

K James, OG Oluwole - The Journal of Gene Medicine, 2024 - Wiley Online Library
Mouse models are used extensively to understand human pathobiology and mechanistic
functions of disease‐associated loci. However, in this review, we investigate the potential of …

迁移侵袭抑制蛋白在肿瘤发生发展中的作用及其临床意义

王超, 孙燕 - 中国肿瘤临床, 2018 - cjco.cn
迁移侵袭抑制蛋白(migration and invasion inhibitory protein, MIIP) 能够与胰岛素样生长因子
结合蛋白2 (insulin-like growth factor binding protein 2, IGFBP2), 组蛋白去乙酰化酶6 (histone …

Predicting Binding Affinity Between MHC-I Receptor and Peptides Based on Molecular Docking and Protein-peptide Interaction Interface Characteristics

S Huang, Y Ding - Letters in Drug Design & Discovery, 2023 - ingentaconnect.com
Background: Predicting protein-peptide binding affinity is one of the leading research
subjects in peptide drug design and repositioning. In previous studies, models constructed …

MIIP gene expression is associated with radiosensitivity in human nasopharyngeal carcinoma cells

HP Zhou, LX Qian, N Zhang, JJ Gu… - Oncology …, 2018 - spandidos-publications.com
The present study aims to investigate the radiosensitization effect of the migration and
invasion inhibitory protein (MIIP) gene on nasopharyngeal carcinoma (NPC) cells. The MIIP …

[图书][B] Antibody effector functions critical to mucosal protection against HIV-1

HM Cheeseman - 2017 - core.ac.uk
Abstract Human Immunodeficiency Virus-1 (HIV-1) is a retrovirus that was identified more
than thirty years ago as the cause of Acquired Immunodeficiency Syndrome (AIDS). The only …