Introduction The rare coagulation disorders may present significant difficulties in diagnosis
and management. In addition, considerable inter‐individual variation in bleeding phenotype …

Rare bleeding disorders (RBDs) comprise inherited deficiencies of factors I (fibrinogen), II
(prothrombin), V, VII, X, XI, and XIII as well as combined factor V+ VIII and vitamin K …

Rare bleeding disorders (RBDs) are a heterogeneous group of coagulation factor
deficiencies that include fibrinogen, prothrombin, α 2-antiplasmin, plasminogen activator …

Clotting Factor deficiencies are rare disorders with variations in clinical presentation and
severity of symptoms ranging from asymptomatic to mild to life-threatening bleeding. Thus …

Combined factor V (FV) and FVIII deficiency (F5F8D) is a rare autosomal-recessive bleeding
disorder caused by mutations in lectin mannose binding-1 (LMAN1) and multiple …

Rare bleeding disorders (RBDs) include the hereditary deficiency of fibrinogen, factor (F) II,
FV, FV+ FVIII, FVII, FX, FXI or FXIII. RBDs do not confer a protective effect against …

ABSTRACT Introduction: Rare bleeding disorders (RBDs) are a heterogeneous group of
bleeding disorders. Consanguineous marriage is the favorite partnership in many …

Introduction Rare coagulation factor deficiencies are less-known disorders with variable
effects on the patient's life. Management of such patients is a challenge due to the paucity of …

Background Coagulation factors, anticoagulants, and fibrinolytic proteins are important for
hemostasis, and mutations affecting these proteins causes some rare inherited bleeding …

Rare inherited coagulation disorders due to the deficiency or dysfunction of coagulation
factors have until recently received less clinical attention than hemophilias and von …