Iron is an essential micronutrient for virtually all living cells. In infectious diseases, both
invading pathogens and mammalian cells including those of the immune system require iron …

Immunometabolism explores how the intracellular metabolic pathways in immune cells can
regulate their function under different micro-environmental and (patho-)-physiological …

The control over iron availability is crucial under homeostatic conditions and even more in
the case of an infection. This results from diverse properties of iron: first, iron is an important …

Production of minute concentrations of superoxide (O 2 radical dot−) and nitrogen monoxide
(nitric oxide, NO radical dot) plays important roles in several aspects of cellular signaling …

Both, mammalian cells and microbes have an essential need for iron, which is required for
many metabolic processes and for microbial pathogenicity. In addition, cross-regulatory …

Iron holds a central position at the host–pathogen interface because mammalian and
microbial cells have an essential demand for the metal, which is required for many metabolic …

Iron deficiency anaemia is one of the most common disorders in the world. Also, one third of
inflammatory bowel disease (IBD) patients suffer from recurrent anaemia. Anaemia has …

Hepcidin controls the levels and distribution of iron, an element whose availability can
influence the outcome of infections. We investigated hepcidin regulation by infection …

Publisher Summary This chapter summarizes the recent knowledge on the production of
cytokines by neutrophils in vitro and in vivo—particularly molecular regulation and other …

Cet article fait une revue de nos connaissances actuelles concernant la structure et la
fonction de la lactoferrine, une protéine liant le fer. Il tente spécialement d'établir une relation …