A survey on computational models for predicting protein–protein interactions

L Hu, X Wang, YA Huang, P Hu… - Briefings in …, 2021 - academic.oup.com
Proteins interact with each other to play critical roles in many biological processes in cells.
Although promising, laboratory experiments usually suffer from the disadvantages of being …

Mobile genetic elements: the agents of open source evolution

LS Frost, R Leplae, AO Summers… - Nature Reviews …, 2005 - nature.com
Horizontal genomics is a new field in prokaryotic biology that is focused on the analysis of
DNA sequences in prokaryotic chromosomes that seem to have originated from other …

Deep graph kernels

P Yanardag, SVN Vishwanathan - Proceedings of the 21th ACM …, 2015 - dl.acm.org
In this paper, we present Deep Graph Kernels, a unified framework to learn latent
representations of sub-structures for graphs, inspired by latest advancements in language …

SCOPe: improvements to the structural classification of proteins–extended database to facilitate variant interpretation and machine learning

JM Chandonia, L Guan, S Lin, C Yu… - Nucleic acids …, 2022 - academic.oup.com
Abstract The Structural Classification of Proteins—extended (SCOPe, https://scop. berkeley.
edu) knowledgebase aims to provide an accurate, detailed, and comprehensive description …

Discriminative embeddings of latent variable models for structured data

H Dai, B Dai, L Song - International conference on machine …, 2016 - proceedings.mlr.press
Kernel classifiers and regressors designed for structured data, such as sequences, trees
and graphs, have significantly advanced a number of interdisciplinary areas such as …

Using deep learning to annotate the protein universe

ML Bileschi, D Belanger, DH Bryant, T Sanderson… - Nature …, 2022 - nature.com
Understanding the relationship between amino acid sequence and protein function is a long-
standing challenge with far-reaching scientific and translational implications. State-of-the-art …

D2P2: database of disordered protein predictions

ME Oates, P Romero, T Ishida, M Ghalwash… - Nucleic acids …, 2012 - academic.oup.com
We present the Database of Disordered Protein Prediction (D2P2), available at http://d2p2.
pro (including website source code). A battery of disorder predictors and their variants, VL …

Comparative protein structure modeling using MODELLER

B Webb, A Sali - Current protocols in bioinformatics, 2016 - Wiley Online Library
Comparative protein structure modeling predicts the three‐dimensional structure of a given
protein sequence (target) based primarily on its alignment to one or more proteins of known …

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

K Arnold, L Bordoli, J Kopp, T Schwede - Bioinformatics, 2006 - academic.oup.com
Motivation: Homology models of proteins are of great interest for planning and analysing
biological experiments when no experimental three-dimensional structures are available …

Protein structure homology modeling using SWISS-MODEL workspace

L Bordoli, F Kiefer, K Arnold, P Benkert, J Battey… - Nature protocols, 2009 - nature.com
Homology modeling aims to build three-dimensional protein structure models using
experimentally determined structures of related family members as templates. SWISS …