Abstract DHEA and DHEA-S have numerous associations with multiple aspects of immune
function and are often characterized as beneficial and supportive of immunocompetence …

Secretory immunoglobulin A (SIgA) is one of the most abundant immunoglobulin subtypes
among mucosa, which plays an indispensable role in the first-line protection against …

Adrenarche, the post-natal rise of DHEA and DHEAS, is unique to humans and the African
Apes. Recent findings have linked DHEA in humans to the development of the left …

Objective Immune function is multifaceted and characterizations based on single biomarkers
may be uninformative or misleading, particularly when considered across ecological …

The androgen dehydroepiandrosterone (DHEA) responds to stress activation, exhibits anti‐
glucocorticoid properties, and modulates immunity in diverse ways, yet little is known of its …

The immunocompetence handicap hypothesis (ICHH) contends that testosterone-
dependent, masculine traits are honest signals of the bearer's ability to withstand …

Individual variation in the age of pubertal onset is linked to physical and mental health, yet
the factors underlying this variation are poorly understood. Life history theory predicts that …

Objectives A core assumption of life history theory and the immunocompetence handicap
hypothesis (ICHH) is that testosterone (T) upregulates energetic investment in mating effort …

Background Previous research on the association between testosterone (T) and immunity
has produced conflicting results. Objectives We address two potential reasons for these …

Aldosterone and cortisone are released in response to physical and psychological stress.
However, aldosterone and cortisone responses in children engaged in physical competition …