Neurogenesis in mammals occurs throughout life in two brain regions: the ventricular–
subventricular zone (V–SVZ) and the subgranular zone (SGZ) of the hippocampal dentate …

The hypothalamic-pituitary-adrenal (HPA) axis and its end-effectors glucocorticoid
hormones play central roles in the adaptive response to numerous stressors that can be …

OBJECTIVE: Severe acute respiratory syndrome (SARS) was the first massive infectious
disease outbreak of the 21st century. However, it is unlikely that this outbreak will be the last …

Obsessive–compulsive disorder (OCD) is a clinically heterogeneous disorder characterized
by multiple, temporally stable symptom dimensions. Preliminary functional neuroimaging …

Exercise promotes hippocampal neurogenesis and dendritic plasticity while stress shows
the opposite effects, suggesting a possible mechanism for exercise to counteract stress …

Mounting evidence indicates that Wnt signaling is relevant to pathophysiology of diverse
mental illnesses including schizophrenia, bipolar disorder, and autism spectrum disorder. In …

There are many indications that neurogenesis is impaired in Parkinson's disease, which
might be due to a lack of dopamine in the subventricular zone. An impairment in …

The maternal brain is remarkably plastic and exhibits multifaceted neural modifications.
Neurogenesis has emerged as one of the mechanisms by which the maternal brain exhibits …

Neuropsychiatric sequalae to coronavirus disease 2019 (COVID-19) infection are beginning
to emerge, like previous Spanish influenza and severe acute respiratory syndrome …

In an effort to better understand and treat mental disorders, the Wnt pathway and adult
hippocampal neurogenesis have received increased attention in recent years. One is a …