Melodic maestros: Unraveling the role of miRNAs in the diagnosis, progression, and drug resistance of malignant pleural mesothelioma

MA Abd-Elmawla, SSA Mageed… - … -Research and Practice, 2023 - Elsevier
Malignant pleural mesothelioma (MPM) is a highly lethal form of pleural cancer
characterized by a scarcity of effective therapeutic interventions, resulting in unfavorable …

Molecular pathogenesis of malignant mesothelioma

Y Sekido - Carcinogenesis, 2013 - academic.oup.com
Malignant mesothelioma (MM) is an aggressive tumor arising primarily from the pleural or
peritoneal cavities. It develops by asbestos exposure after a long latency, which is …

[HTML][HTML] Restoring expression of miR-16: a novel approach to therapy for malignant pleural mesothelioma

G Reid, ME Pel, MB Kirschner, YY Cheng… - Annals of …, 2013 - Elsevier
Background Malignant pleural mesothelioma (MPM) is recalcitrant to treatment and new
approaches to therapy are needed. Reduced expression of miR-15/16 in a range of cancer …

MicroRNA regulation of core apoptosis pathways in cancer

RT Lima, S Busacca, GM Almeida, G Gaudino… - European journal of …, 2011 - Elsevier
Recent research has demonstrated that microRNAs (miRNAs) are key regulators of many
cell processes often deregulated in cancer, including apoptosis. Indeed, it is becoming clear …

The peripheral blood mononuclear cell microRNA signature of coronary artery disease

M Hoekstra, CAC van der Lans, B Halvorsen… - Biochemical and …, 2010 - Elsevier
BACKGROUND: MicroRNAs are being used in the oncology field to characterize tumors and
predict the survival of cancer patients. Here, we explored the potential of microRNAs as …

Cancer genome sequencing: a review

ER Mardis, RK Wilson - Human molecular genetics, 2009 - academic.oup.com
A genomic era of cancer studies is developing rapidly, fueled by the emergence of next-
generation sequencing technologies that provide exquisite sensitivity and resolution. This …

MicroRNA profiling in cancer

R Munker, GA Calin - Clinical science, 2011 - portlandpress.com
The diagnosis of cancer has undergone major changes in the last 40 years. Once based
purely on morphology, diagnosis has come to incorporate immunological, cytogenetic and …

Detection of circulating tumor cells in peripheral blood from patients with gastric cancer using microRNA as a marker

H Zhou, JM Guo, YR Lou, XJ Zhang, FD Zhong… - Journal of molecular …, 2010 - Springer
Recently, the detection of occult cancer cells in peripheral blood has received a great deal of
attention regarding the prediction of postoperative cancer recurrence and for novel …

Combinations of serum prostate-specific antigen and plasma expression levels of let-7c, miR-30c, miR-141, and miR-375 as potential better diagnostic biomarkers for …

D Kachakova, A Mitkova, E Popov, I Popov… - DNA and cell …, 2015 - liebertpub.com
In the current study, expression levels of let-7c, miR-30c, miR-141, and miR-375 in plasma
from 59 prostate cancer (PC) patients with different clinicopathological characteristics and …

Prognostic role of microRNA‐21 in various carcinomas: a systematic review and meta‐analysis

X Fu, Y Han, Y Wu, X Zhu, X Lu, F Mao… - European journal of …, 2011 - Wiley Online Library
Eur J Clin Invest 2011; 41 (11): 1245–1253 Abstract Background Recent studies have
shown that microRNAs (miRNA) could play a potential role as diagnostic and prognostic …