[HTML][HTML] SARS-CoV-2 spike opening dynamics and energetics reveal the individual roles of glycans and their collective impact

YT Pang, A Acharya, DL Lynch, A Pavlova… - Communications …, 2022 - nature.com
The trimeric spike (S) glycoprotein, which protrudes from the SARS-CoV-2 viral envelope,
binds to human ACE2, initiated by at least one protomer's receptor binding domain (RBD) …

SARS-CoV-2 spike protein mutations and escape from antibodies: a computational model of epitope loss in variants of concern

A Triveri, SA Serapian, F Marchetti… - Journal of Chemical …, 2021 - ACS Publications
The SARS-CoV-2 spike (S) protein is exposed on the viral surface and is the first point of
contact between the virus and the host. For these reasons it represents the prime target for …