Antiretroviral therapy (ART), while essential in combatting tuberculosis (TB) and HIV
coinfection, is often complicated by the TB-associated immune reconstitution inflammatory …

Tuberculosis (TB) is still a severe public health problem; the current diagnostic tests have
limitations that delay treatment onset. Lipoarabinomannan (LAM) is a glycolipid that is a …

New tuberculosis (TB) diagnostics are at a crossroads: their development, evaluation, and
implementation is severely damaged by resource diversion due to COVID-19. Yet several …

Background Tuberculous meningitis (TBM) has a high fatality rate, with inadequate
diagnostic tests being a major contributor. The rollout of Xpert MTB/Rif and Xpert MTB/RIF …

Children affected by tuberculous meningitis (TBM), as well as their families, have needs that
lie at the intersections between the tuberculosis and meningitis clinical, research, and policy …

Tuberculosis lymphadenitis (TBL) is the most common extrapulmonary tuberculosis (EPTB)
manifestation. Xpert MTB/RIF Ultra (Ultra) is a World Health Organization-endorsed …

Background Despite expanded access to antiretroviral therapy (ART) and the rollout of the
World Health Organization's (WHO)'test‐and‐treat'strategy, the proportion of people with HIV …

Background Diagnostic delays for tuberculosis are common, with high resultant mortality.
Urine-Xpert Ultra (Cepheid) could improve time to diagnosis of tuberculosis disease and …

Background: This study aimed to assess whether Xpert MTB/RIF Ultra (Xpert Ultra) can
effectively diagnose tuberculosis meningitis (TBM) and to simultaneously compare its …

Human immunodeficiency virus (HIV)–associated cryptococcal meningitis continues to have
acute mortality rates in excess of 15% even in well-resourced settings [1, 2]. Rapid …