Antioxidant properties of anthocyanins and their mechanism of action in atherosclerosis
Atherosclerosis develops due to lipid accumulation in the arterial wall and sclerosis as result
of increased hyperlipidemia, oxidative stress, lipid oxidation, and protein oxidation …
of increased hyperlipidemia, oxidative stress, lipid oxidation, and protein oxidation …
[HTML][HTML] The role of lipids and lipoproteins in atherosclerosis
MRF Linton, PG Yancey, SS Davies, WG Jerome… - Endotext …, 2019 - ncbi.nlm.nih.gov
Atherosclerosis is the underlying cause of heart attack and stroke. Early observations that
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …
[HTML][HTML] COVID‐19—Associated dyslipidemia: Implications for mechanism of impaired resolution and novel therapeutic approaches
AV Sorokin, SK Karathanasis, ZH Yang… - The FASEB …, 2020 - ncbi.nlm.nih.gov
The current coronavirus disease 2019 (COVID‐19) pandemic presents a global challenge
for managing acutely ill patients and complications from viral infection. Systemic …
for managing acutely ill patients and complications from viral infection. Systemic …
[HTML][HTML] Lipoproteins and lipids in cardiovascular disease: from mechanistic insights to therapeutic targeting
J Soppert, M Lehrke, N Marx, J Jankowski… - Advanced drug delivery …, 2020 - Elsevier
With cardiovascular disease being the leading cause of morbidity and mortality worldwide,
effective and cost-efficient therapies to reduce cardiovascular risk are highly needed. Lipids …
effective and cost-efficient therapies to reduce cardiovascular risk are highly needed. Lipids …
[HTML][HTML] Antioxidative activity of high-density lipoprotein (HDL): Mechanistic insights into potential clinical benefit
F Brites, M Martin, I Guillas, A Kontush - BBA clinical, 2017 - Elsevier
Uptake of low-density lipoprotein (LDL) particles by macrophages represents a key step in
the development of atherosclerotic plaques, leading to the foam cell formation. Chemical …
the development of atherosclerotic plaques, leading to the foam cell formation. Chemical …
HDL and cardiovascular disease: atherogenic and atheroprotective mechanisms
The lipoprotein HDL has two important roles: first, it promotes reverse cholesterol transport,
and second, it modulates inflammation. Epidemiological studies show that HDL-cholesterol …
and second, it modulates inflammation. Epidemiological studies show that HDL-cholesterol …
Antiinflammatory properties of HDL
There are several well-documented functions of high-density lipoprotein (HDL) that may
explain the ability of these lipoproteins to protect against atherosclerosis. The best …
explain the ability of these lipoproteins to protect against atherosclerosis. The best …
Cardiovascular risk in rheumatoid arthritis: recent advances in the understanding of the pivotal role of inflammation, risk predictors and the impact of treatment
Risk of cardiovascular (CV) disease is increased among RA patients. High inflammatory
burden associated with RA appears to be a key driver of the increased cardiovascular risk …
burden associated with RA appears to be a key driver of the increased cardiovascular risk …
Functionally defective high-density lipoprotein: a new therapeutic target at the crossroads of dyslipidemia, inflammation, and atherosclerosis
A Kontush, MJ Chapman - Pharmacological reviews, 2006 - ASPET
High-density lipoproteins (HDL) possess key atheroprotective biological properties,
including cellular cholesterol efflux capacity, and anti-oxidative and anti-inflammatory …
including cellular cholesterol efflux capacity, and anti-oxidative and anti-inflammatory …
Ambient particulate pollutants in the ultrafine range promote early atherosclerosis and systemic oxidative stress
JA Araujo, B Barajas, M Kleinman, X Wang… - Circulation …, 2008 - Am Heart Assoc
Air pollution is associated with significant adverse health effects, including increased
cardiovascular morbidity and mortality. Exposure to particulate matter with an aerodynamic …
cardiovascular morbidity and mortality. Exposure to particulate matter with an aerodynamic …