Antioxidant properties of anthocyanins and their mechanism of action in atherosclerosis

C Garcia, CN Blesso - Free Radical Biology and Medicine, 2021 - Elsevier
Atherosclerosis develops due to lipid accumulation in the arterial wall and sclerosis as result
of increased hyperlipidemia, oxidative stress, lipid oxidation, and protein oxidation …

[HTML][HTML] The role of lipids and lipoproteins in atherosclerosis

MRF Linton, PG Yancey, SS Davies, WG Jerome… - Endotext …, 2019 - ncbi.nlm.nih.gov
Atherosclerosis is the underlying cause of heart attack and stroke. Early observations that
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …

[HTML][HTML] COVID‐19—Associated dyslipidemia: Implications for mechanism of impaired resolution and novel therapeutic approaches

AV Sorokin, SK Karathanasis, ZH Yang… - The FASEB …, 2020 - ncbi.nlm.nih.gov
The current coronavirus disease 2019 (COVID‐19) pandemic presents a global challenge
for managing acutely ill patients and complications from viral infection. Systemic …

[HTML][HTML] Lipoproteins and lipids in cardiovascular disease: from mechanistic insights to therapeutic targeting

J Soppert, M Lehrke, N Marx, J Jankowski… - Advanced drug delivery …, 2020 - Elsevier
With cardiovascular disease being the leading cause of morbidity and mortality worldwide,
effective and cost-efficient therapies to reduce cardiovascular risk are highly needed. Lipids …

[HTML][HTML] Antioxidative activity of high-density lipoprotein (HDL): Mechanistic insights into potential clinical benefit

F Brites, M Martin, I Guillas, A Kontush - BBA clinical, 2017 - Elsevier
Uptake of low-density lipoprotein (LDL) particles by macrophages represents a key step in
the development of atherosclerotic plaques, leading to the foam cell formation. Chemical …

HDL and cardiovascular disease: atherogenic and atheroprotective mechanisms

M Navab, ST Reddy, BJ Van Lenten… - Nature Reviews …, 2011 - nature.com
The lipoprotein HDL has two important roles: first, it promotes reverse cholesterol transport,
and second, it modulates inflammation. Epidemiological studies show that HDL-cholesterol …

Antiinflammatory properties of HDL

PJ Barter, S Nicholls, KA Rye… - Circulation …, 2004 - Am Heart Assoc
There are several well-documented functions of high-density lipoprotein (HDL) that may
explain the ability of these lipoproteins to protect against atherosclerosis. The best …

Cardiovascular risk in rheumatoid arthritis: recent advances in the understanding of the pivotal role of inflammation, risk predictors and the impact of treatment

E Choy, K Ganeshalingam, AG Semb… - …, 2014 - academic.oup.com
Risk of cardiovascular (CV) disease is increased among RA patients. High inflammatory
burden associated with RA appears to be a key driver of the increased cardiovascular risk …

Functionally defective high-density lipoprotein: a new therapeutic target at the crossroads of dyslipidemia, inflammation, and atherosclerosis

A Kontush, MJ Chapman - Pharmacological reviews, 2006 - ASPET
High-density lipoproteins (HDL) possess key atheroprotective biological properties,
including cellular cholesterol efflux capacity, and anti-oxidative and anti-inflammatory …

Ambient particulate pollutants in the ultrafine range promote early atherosclerosis and systemic oxidative stress

JA Araujo, B Barajas, M Kleinman, X Wang… - Circulation …, 2008 - Am Heart Assoc
Air pollution is associated with significant adverse health effects, including increased
cardiovascular morbidity and mortality. Exposure to particulate matter with an aerodynamic …