Human papillomavirus associated cervical lesion: pathogenesis and therapeutic interventions

J Ye, L Zheng, Y He, X Qi - MedComm, 2023 - Wiley Online Library
Human papillomavirus (HPV) is the most prevalent sexually transmitted virus globally.
Persistent high‐risk HPV infection can result in cervical precancerous lesions and cervical …

[HTML][HTML] Regeneration and anti-inflammatory effects of stem cells and their extracellular vesicles in gynecological diseases

X Zheng, D Zhao, Y Liu, Y Jin, T Liu, H Li… - Biomedicine & …, 2023 - Elsevier
There are many gynecological diseases, among which breast cancer (BC), cervical cancer
(CC), endometriosis (EMs), and polycystic ovary syndrome (PCOS) are common and difficult …

HPV16 E6-Activated OCT4 Promotes Cervical Cancer Progression by Suppressing p53 Expression via Co-Repressor NCOR1

S Shu, Z Li, L Liu, X Ying, Y Zhang, T Wang… - Frontiers in …, 2022 - frontiersin.org
Human papillomaviruses (HPV), mainly HPV16 and HPV18, of high-risk classification are
involved in cervical cancer carcinogenesis and progression. Octamer-binding transcription …

[HTML][HTML] miR-326 inhibits the cell proliferation and cancer stem cell-like property of cervical cancer in vitro and oncogenesis in vivo via targeting TCF4

J Zhang, H He, K Wang, Y Xie, Z Yang… - Annals of …, 2020 - ncbi.nlm.nih.gov
Background Cervical cancer ranks as one of the most prevalent female malignancies
globally, and its treatment with new targets has been the focus of current research. The …

Diagnostic and Prognostic Implications of Cancer Stem Cell Transcription Factors

S Patil, F Islam, V Gopalan - Cancer Stem Cells: Basic Concept and …, 2023 - Springer
Cancer stem cells (CSCs) are a subpopulation of malignant cells with self-renewing
capacity, hence being vital in the areas of tumour initiation and progression, therapeutic …

[HTML][HTML] miR-145 通过调控人子宫内膜基质细胞OCT4 的表达促进子宫内膜异位症的发展机制

张素仙, 冯莉嵋, 伍路, 杨绍艳, 赵庆华 - 昆明医科大学学报, 2022 - kyxuebao.kmmu.edu.cn
目的通过体外细胞试验探讨miR-145 在子宫内膜异位症(Endometriosis, EMs) 中的调控机制.
方法蛋白印迹检测OCT4 等相关蛋白的表达水平, 通过相关分析和双荧光素酶报告试验用于评估 …

miR-145 Regulates the Expression of OCT4 in Human Endometrial Stromal Cells and Promotes the Development of Endometriosis

S ZHANG, F Limei, WU Lu, Y Shaoyan… - 昆明医科大学 …, 2022 - kyxuebao.kmmu.edu.cn
Objective To further explore the regulatory mechanism of miR-145 in Endometriosis (EMs)
through cell experiments. Methods miR-145 or octamer-binding transcription factor 4 (OCT4) …