Narcolepsy is a rare brain disorder that reflects a selective loss or dysfunction of orexin (also
known as hypocretin) neurons of the lateral hypothalamus. Narcolepsy type 1 (NT1) is …

Abstract Narcolepsy type 1 (NT1) is a chronic sleep disorder resulting from the loss of a
small population of hypothalamic neurons that produce wake-promoting hypocretin (HCRT; …

See Mander et al.(doi: 10.1093/awx174) for a scientific commentary on this article. Sleep
deprivation increases amyloid-β, suggesting that chronically disrupted sleep may promote …

Insomnia is highly prevalent in clinical practice, occurring in up to 50% of primary care
patients. Insomnia can present independently or alongside other medical conditions or …

Narcolepsy type 1 (NT1) is a sleep disorder caused by a loss of orexinergic neurons.
Narcolepsy type 2 (NT2) is heterogeneous; affected individuals typically have normal orexin …

Abstract Analysis of sleep for the diagnosis of sleep disorders such as Type-1 Narcolepsy
(T1N) currently requires visual inspection of polysomnography records by trained scoring …

Narcolepsy is the most common neurological cause of chronic sleepiness. The discovery
about 20 years ago that narcolepsy is caused by selective loss of the neurons producing …

The aim of this European initiative is to facilitate a structured discussion to improve the next
edition of the International Classification of Sleep Disorders (ICSD), particularly the chapter …

NEW case descriptions offer additional practice in working your way through real-life
scenarios to reach an accurate diagnosis and an effective treatment plan for neurologic …

Vigilance is a term with varied definitions but the most common usage is sustained attention
or tonic alertness. This usage of vigilance implies both the degree of arousal on the sleep …