In 2007, 1179 papers were published that involved the application of optical biosensors.
Reported developments in instrument hardware, assay design, and immobilization …

The nuclear export of mRNA, in which Mex67–Mtr2 mediates movement of mature
transcripts through nuclear pores, represents the culmination of the nuclear portion of the …

The export of mRNA from nucleus to cytoplasm requires the conserved and essential
transcription and export (TREX) complex (THO–UAP56/DDX39B–ALYREF). TREX …

Biogenesis of eukaryotic messenger ribonucleoprotein complexes (mRNPs) involves the
synthesis, splicing, and 3′ processing of pre-mRNA, and the assembly of mature mRNPs …

In addition to their established roles in nucleocytoplasmic transport, the intimate association
of nuclear pore complexes (NPCs) with chromatin has long led to speculation that these …

The evolutionary 'decision'to store genetic information away from the place of protein
synthesis, in a separate compartment, has forced eukaryotic cells to establish a system to …

The THO complex is a key factor in co‐transcriptional formation of export‐competent
messenger ribonucleoprotein particles, yet its structure and mechanism of chromatin …

The transcription of mRNA is tightly coupled to the concomitant recruitment of mRNA
processing and export factors, resulting in the formation of mature and export competent …

From decades of genetic and molecular studies, there is no doubt about the foremost
importance of genes in defining organism and cell identity, in healthy and in pathological …

Transcription is the foremost regulatory point during the process of producing a functional
protein. Not only specific genes need to be turned on and off according to growth and …