The rapid emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants that evade immunity elicited by vaccination has placed an imperative on the …

From the beginning of the COVID-19 pandemic, children have exhibited different
susceptibility to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …

Recognition of antigens by T cell receptors (TCRs) and B cell receptors (BCRs) is a key step
in lymphocyte activation. T and B cells mediate adaptive immune responses, which protect …

Abstract The SARS-CoV-2 Omicron variant evades most currently approved neutralizing
antibodies (nAbs) and caused drastic decrease of plasma neutralizing activity elicited by …

The ability of the human immune system to generate antibodies to any given antigen can be
strongly influenced by immunoglobulin V-gene allelic polymorphisms. However, previous …

Striking antibody evasion by emerging circulating severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) variants drives the identification of broadly neutralizing …

The pairing of antibody genes IGHV2-5/IGLV2-14 is established as a public immune
response that potently cross-neutralizes SARS-CoV-2 variants, including Omicron, by …

The rapid emergence of SARS-CoV-2 variants that evade immunity to vaccination has
placed a global health imperative on the development of therapeutic countermeasures that …

This study reports the isolation and characterization of a human monoclonal antibody (mAb)
called 19n01. This mAb was isolated by using single-cell RNAseq of B cells from donors …

Immunoglobulin (IG) genes, encoding B cell receptors (BCRs), are fundamental components
of the mammalian immune system, which evolved to recognize the diverse antigenic …