[HTML][HTML] Zebrafish as a model for inflammation and drug discovery
Highlights•Zebrafish are a useful tool for screening new drugs for inflammation.•This teleost
shares several inflammatory mediators and receptors with mammals.•The real-time …
shares several inflammatory mediators and receptors with mammals.•The real-time …
Modelling viral infections using zebrafish: innate immune response and antiviral research
Zebrafish possess a highly developed immune system that is remarkably similar to the
human one. Therefore, it is expected that the majority of the signalling pathways and …
human one. Therefore, it is expected that the majority of the signalling pathways and …
Luteolin, a promising quorum quencher mitigates virulence factors production in Pseudomonas aeruginosa-In vitro and In vivoapproach
Pseudomonas aeruginosa (PA) is an opportunistic pathogen that causes healthcare-
associated infection and high mortality in immunocompromised patients. It produces several …
associated infection and high mortality in immunocompromised patients. It produces several …
[HTML][HTML] High-resolution, 3D imaging of the zebrafish gill-associated lymphoid tissue (GIALT) reveals a novel lymphoid structure, the amphibranchial lymphoid tissue
AS Dalum, A Kraus, S Khan, E Davydova… - Frontiers in …, 2021 - frontiersin.org
The zebrafish is extensively used as an animal model for human and fish diseases.
However, our understanding of the structural organization of its immune system remains …
However, our understanding of the structural organization of its immune system remains …
A review of cumulative toxic effects of environmental endocrine disruptors on the zebrafish immune system: Characterization methods, toxic effects and mechanisms
Z Li, M Li, D Li, Y Chen, W Feng, T Zhao, L Yang… - Environmental …, 2024 - Elsevier
Environmental endocrine disrupting chemicals (EDCs), are a type of exogenous organic
pollutants, are ubiquitous in natural aquatic environments. Currently, in addition to …
pollutants, are ubiquitous in natural aquatic environments. Currently, in addition to …
Nanodelivery systems as new tools for immunostimulant or vaccine administration: targeting the fish immune system
Fish disease treatments have progressed significantly over the last few years and have
moved from the massive use of antibiotics to the development of vaccines mainly based on …
moved from the massive use of antibiotics to the development of vaccines mainly based on …
Crab (Charybdis natator) exoskeleton derived chitosan nanoparticles for the in vivo delivery of poorly water-soluble drug: Ibuprofen
The study aims to extract and purify chitosan (CS) from the exoskeleton of crab (C. natator)
and develop ibuprofen (IBU) encapsulated CS nanoparticles (IBU-CSNPs). Analysis of …
and develop ibuprofen (IBU) encapsulated CS nanoparticles (IBU-CSNPs). Analysis of …
Exploring the HIFs, buts and maybes of hypoxia signalling in disease: lessons from zebrafish models
ABSTRACT A low level of tissue oxygen (hypoxia) is a physiological feature of a wide range
of diseases, from cancer to infection. Cellular hypoxia is sensed by oxygen-sensitive …
of diseases, from cancer to infection. Cellular hypoxia is sensed by oxygen-sensitive …
Comparative study in zebrafish and medaka unravels the mechanisms of tissue regeneration
Tissue regeneration has been in the spotlight of research for its fascinating nature and
potential applications in human diseases. The trait of regenerative capacity occurs diversely …
potential applications in human diseases. The trait of regenerative capacity occurs diversely …
Enhancing innate antiviral immune responses in rainbow trout by double stranded RNA delivered with cationic phytoglycogen nanoparticles
TN Alkie, J de Jong, K Jenik, KM Klinger… - Scientific Reports, 2019 - nature.com
Innate immunity is induced when pathogen-associated molecular patterns (PAMPs) bind
host pattern recognition receptors (PRRs). Polyinosinic: polycytidylic acid [poly (I: C)] is a …
host pattern recognition receptors (PRRs). Polyinosinic: polycytidylic acid [poly (I: C)] is a …