There is increasing awareness of bronchiectasis in children and adolescents, a chronic
pulmonary disorder associated with poor quality of life for the child/adolescent and their …

Accurate and timely diagnosis of primary immunodeficiencies (PID) is an ongoing effort.
Individuals with PID can be severely impacted by their disease and many experience …

Background Primary immunodeficiencies (PI), which include more than 450 single-gene
inborn errors of immunity and may affect up to 1% of the population, are genetic disorders …

Objective Much has been invested in big data analytics to improve health and reduce costs.
However, it is unknown whether these investments have achieved the desired goals. We …

Background Primary immunodeficiency diseases (PIDD) are a group of immune-related
disorders that have a current median delay of diagnosis between 6 and 9 years. Early …

Artificial and augmented intelligence (AI) and machine learning (ML) methods are
expanding into the health care space. Big data are increasingly used in patient care …

Background Primary immunodeficiency diseases represent an expanding set of
heterogeneous conditions which are difficult to recognize clinically. Diagnostic rates outside …

Background Identification of patients with underlying inborn errors of immunity and inherent
susceptibility to infection remains challenging. The ensuing protracted diagnostic odyssey …

This review highlights use of computational methods for analysis of large datasets across
the spectrum of research and clinical care for patients with immunological disorders. Here …

Background: Primary immunodeficiencies (PIs) are a set of heterogeneous chronic disorders
characterized by immune dysfunction. They are diagnostically challenging because of their …