Bacteria in the genus Brucella are important human and veterinary pathogens. The abortion
and infertility they cause in food animals produce economic hardships in areas where the …

Background The pure culture of prokaryotes remains essential to elucidating the role of
these organisms. Scientists have reasoned that hard to cultivate microorganisms might grow …

Intracellular bacterial pathogens (IBPs) invade and replicate in different cell types including
immune cells, in particular of the innate immune system (IIS) during infection in the acute …

Intracellular bacterial pathogens exploit host cell resources to replicate and survive inside
the host. Targeting these host systems is one promising approach to developing novel …

Brucella abortus is a facultative intracellular pathogen causing a severe zoonotic disease
worldwide. The two-component regulatory system (TCS) BvrR/BvrS of B. abortus is …

Brucellosis is one of the most widespread bacterial zoonoses worldwide. Here, our aim was
to identify the effector mechanisms controlling the early stages of intranasal infection with …

The cell nucleus is a primary target for intracellular bacterial pathogens to counteract
immune responses and hijack host signalling pathways to cause disease. Here we identify …

The ability of Staphylococcus aureus and other pathogens to consume glucose is critical
during infection. However, glucose consumption increases the cellular demand for …

Erythritol is an important nutrient for several α-2 Proteobacteria, including N2-fixing plant
endosymbionts and Brucella, a worldwide pathogen that finds this four-carbon polyol in …

Brucella is an intracellular parasitic pathogen that causes the worldwide zoonotic disease
brucellosis. The type IV secretion system (T4SS) is utilized to secrete various effectors to …