[HTML][HTML] Digital biomarkers in multiple sclerosis

A Dillenseger, ML Weidemann, K Trentzsch, H Inojosa… - Brain sciences, 2021 - mdpi.com
For incurable diseases, such as multiple sclerosis (MS), the prevention of progression and
the preservation of quality of life play a crucial role over the entire therapy period. In MS …

Eye tracking metrics to screen and assess cognitive impairment in patients with neurological disorders

L Tao, Q Wang, D Liu, J Wang, Z Zhu, L Feng - Neurological Sciences, 2020 - Springer
Purpose of review Eye tracking is a powerful method to investigate the relationship between
behavior and neural mechanisms. In recent years, eye movement analysis has been used in …

[HTML][HTML] Eye movement abnormalities in multiple sclerosis: pathogenesis, modeling, and treatment

A Serra, CG Chisari, M Matta - Frontiers in neurology, 2018 - frontiersin.org
Multiple sclerosis (MS) commonly causes eye movement abnormalities that may have a
significant impact on patients' disability. Inflammatory demyelinating lesions, especially …

A novel eye-movement impairment in multiple sclerosis indicating widespread cortical damage

JA Nij Bijvank, SN Hof, SE Prouskas, MM Schoonheim… - Brain, 2023 - academic.oup.com
In multiple sclerosis, remyelination trials have yet to deliver success like that achieved for
relapse rates with disease course modifying treatment trials. The challenge is to have a …

[HTML][HTML] Eye movement alterations in post-COVID-19 condition: A proof-of-concept study

C García Cena, MC Costa, R Saltarén Pazmiño… - Sensors, 2022 - mdpi.com
There is much evidence pointing out eye movement alterations in several neurological
diseases. To the best of our knowledge, this is the first video-oculography study describing …

The nature of verbal memory impairment in multiple sclerosis: a list-learning and meta-analytic study

JM Lafosse, SM Mitchell, JR Corboy… - Journal of the …, 2013 - cambridge.org
The primary purpose of this study was to test the hypothesis that multiple sclerosis (MS)
patients have impaired acquisition rather than a retrieval deficit. Verbal memory impairment …

Antisaccade performance in patients with multiple sclerosis

J Fielding, T Kilpatrick, L Millist, O White - Cortex, 2009 - Elsevier
Commonly used measures of disability in patients with Multiple sclerosis (MS) inadequately
reflect disease severity and progression. Further, cognitive deficits experienced by up to …

Cognition and eye movements: assessment of cerebral dysfunction

OB White, J Fielding - Journal of Neuro-ophthalmology, 2012 - journals.lww.com
Background: Many neurological disorders show deficits in ocular motor function. In the past,
evaluation has been limited to assessing abnormalities largely generated by pathology of …

Ocular motor signatures of cognitive dysfunction in multiple sclerosis

J Fielding, M Clough, S Beh, L Millist, D Sears… - Nature Reviews …, 2015 - nature.com
The anatomical and functional overlap between ocular motor command circuitry and the
higher-order networks that form the scaffolding for cognition makes for a compelling …

Ocular motor measures of cognitive dysfunction in multiple sclerosis I: inhibitory control

M Clough, L Millist, N Lizak, S Beh, TC Frohman… - Journal of …, 2015 - Springer
Our ability to control and inhibit behaviours that are inappropriate, unsafe, or no longer
required is crucial for functioning successfully in complex environments. Here, we …