Alcohol-associated hepatitis

R Bataller, JP Arab, VH Shah - New England Journal of Medicine, 2022 - Mass Medical Soc
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Extracellular vesicles as biomarkers in liver diseases: a clinician's point of view

S Thietart, PE Rautou - Journal of hepatology, 2020 - Elsevier
Extracellular vesicles are membrane-bound vesicles containing proteins, lipids, RNAs and
microRNAs. They can originate from both healthy and stressed cells, and provide a …

[HTML][HTML] Isolation and analysis methods of extracellular vesicles (EVs)

Z Zhao, H Wijerathne, AK Godwin… - Extracellular vesicles and …, 2021 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) have been recognized as an evolving biomarker within the
liquid biopsy family. While carrying both host cell proteins and different types of RNAs, EVs …

Pathophysiology of decompensated cirrhosis: Portal hypertension, circulatory dysfunction, inflammation, metabolism and mitochondrial dysfunction

C Engelmann, J Clària, G Szabo, J Bosch… - Journal of …, 2021 - Elsevier
Patients with acutely decompensated cirrhosis have a dismal prognosis and frequently
progress to acute-on-chronic liver failure, which is characterised by hepatic and extrahepatic …

The Role of Endoplasmic Reticulum in Lipotoxicity during MASLD Pathogenesis

N Venkatesan, LC Doskey, H Malhi - The American Journal of Pathology, 2023 - Elsevier
Perturbations in lipid and protein homeostasis induce endoplasmic reticulum (ER) stress in
metabolic-dysfunction-associated steatotic liver disease (MASLD), formerly known as …

Targeted extracellular vesicle delivery systems employing superparamagnetic iron oxide nanoparticles

Z Zhuo, J Wang, Y Luo, R Zeng, C Zhang, W Zhou… - Acta biomaterialia, 2021 - Elsevier
In the past decade, the study of extracellular vesicles (EVs), especially exosomes (50–150
nm) have attracted growing interest in numerous areas of cancer and tissue regeneration …

[HTML][HTML] Alcohol use disorder and alcohol-associated liver disease

R Ramkissoon, VH Shah - Alcohol research: current reviews, 2022 - ncbi.nlm.nih.gov
This article is part of a Festschrift commemorating the 50th anniversary of the National
Institute on Alcohol Abuse and Alcoholism (NIAAA). Established in 1970, first as part of the …

Role of extracellular vesicles in liver diseases and their therapeutic potential

E Kostallari, S Valainathan, L Biquard, VH Shah… - Advanced drug delivery …, 2021 - Elsevier
More than eight hundred million people worldwide have chronic liver disease, with two
million deaths per year. Recurring liver injury results in fibrogenesis, progressing towards …

Recent advances in understanding of pathogenesis of alcohol-associated liver disease

X Wu, X Fan, T Miyata, A Kim… - Annual Review of …, 2023 - annualreviews.org
Alcohol-associated liver disease (ALD) is one of the major diseases arising from chronic
alcohol consumption and is one of the most common causes of liver-related morbidity and …

Role of gut bacterial and non-bacterial microbiota in alcohol-associated liver disease: Molecular mechanisms, biomarkers, and therapeutic prospective

N Zafari, M Velayati, M Fahim, M Maftouh, G Pourali… - Life Sciences, 2022 - Elsevier
Alcohol-associated liver disease (ALD) comprises a spectrum of liver diseases that include:
steatosis to alcohol-associated hepatitis, cirrhosis, and ultimately hepatocellular carcinoma …