Pathogenesis and therapeutic mechanisms in immune thrombocytopenia (ITP)
Immune thrombocytopenia (ITP) is a complex autoimmune disease characterized by low
platelet counts. The pathogenesis of ITP remains unclear although both antibody-mediated …
platelet counts. The pathogenesis of ITP remains unclear although both antibody-mediated …
Pathogenesis of immune thrombocytopenia
S Audia, M Mahévas, M Samson, B Godeau… - Autoimmunity …, 2017 - Elsevier
Immune thrombocytopenia (ITP) is a rare autoimmune disease due to an abnormal T cell
response, notably supported by splenic T follicular helper cells, that stimulates the …
response, notably supported by splenic T follicular helper cells, that stimulates the …
Emerging concepts in immune thrombocytopenia
M Swinkels, M Rijkers, J Voorberg… - Frontiers in …, 2018 - frontiersin.org
Immune thrombocytopenia (ITP) is an autoimmune disease defined by low platelet counts
which presents with an increased bleeding risk. Several genetic risk factors (eg …
which presents with an increased bleeding risk. Several genetic risk factors (eg …
The ITP syndrome: pathogenic and clinical diversity
DB Cines, JB Bussel, HA Liebman… - Blood, The Journal of …, 2009 - ashpublications.org
Immune thrombocytopenia (ITP) is mediated by platelet autoantibodies that accelerate
platelet destruction and inhibit their production. Most cases are considered idiopathic …
platelet destruction and inhibit their production. Most cases are considered idiopathic …
Cellular immune dysfunction in immune thrombocytopenia (ITP)
Over the past decades, a wealth of information has been reported about the pathogenic
features of immune thrombocytopenia (ITP). To this day, however, it is unclear whether the …
features of immune thrombocytopenia (ITP). To this day, however, it is unclear whether the …
Immune thrombocytopenic purpura (ITP) associated with vaccinations: a review of reported cases
C Perricone, F Ceccarelli, G Nesher, E Borella… - Immunologic …, 2014 - Springer
Immune thrombocytopenic purpura (ITP) is an autoimmune condition characterized by low
platelet count with mucocutaneous and other bleedings. Clinical manifestations may range …
platelet count with mucocutaneous and other bleedings. Clinical manifestations may range …
Defective regulatory B-cell compartment in patients with immune thrombocytopenia
B lymphocytes producing antiplatelet autoantibodies play a major role in autoimmune
thrombocytopenia (ITP). However, certain B cells, including the human CD19+ …
thrombocytopenia (ITP). However, certain B cells, including the human CD19+ …
Serum levels of beta2-microglobulin and free light chains of immunoglobulins are associated with systemic disease activity in primary Sjögren's syndrome. Data at …
JE Gottenberg, R Seror, C Miceli-Richard… - PloS one, 2013 - journals.plos.org
Objectives To analyze the clinical and immunological characteristics at enrollment in a large
prospective cohort of patients with primary Sjögren's syndrome (pSS) and to investigate the …
prospective cohort of patients with primary Sjögren's syndrome (pSS) and to investigate the …
ITP: a historical perspective
R Stasi, AC Newland - British journal of haematology, 2011 - Wiley Online Library
A clinical syndrome of bleeding and purpura consistent with a diagnosis of immune
thrombocytopenia (ITP) was described by Werlhof long before platelets were identified as …
thrombocytopenia (ITP) was described by Werlhof long before platelets were identified as …
Advances in diagnosis and treatments for immune thrombocytopenia
S Nomura - Clinical Medicine Insights: Blood Disorders, 2016 - journals.sagepub.com
Immune thrombocytopenia (ITP) is an acquired hemorrhagic condition characterized by the
accelerated clearance of platelets caused by antiplatelet autoantibodies. A platelet count in …
accelerated clearance of platelets caused by antiplatelet autoantibodies. A platelet count in …