Global Cancer Statistics 2022: the trends projection analysis

BS Chhikara, K Parang - Chemical Biology Letters, 2023 - pubs.thesciencein.org
Cancer is one of the most fatal diseases of recent times that causes several deaths every
year. The disease variations in different parts of the world, the impact of available medical …

[HTML][HTML] A global review on short peptides: frontiers and perspectives

V Apostolopoulos, J Bojarska, TT Chai, S Elnagdy… - Molecules, 2021 - mdpi.com
Peptides are fragments of proteins that carry out biological functions. They act as signaling
entities via all domains of life and interfere with protein-protein interactions, which are …

[HTML][HTML] Recent advances in cell penetrating peptide-based anticancer therapies

J Habault, JL Poyet - Molecules, 2019 - mdpi.com
Cell-penetrating-peptides (CPPs) are small amino-acid sequences characterized by their
ability to cross cellular membranes. They can transport various bioactive cargos inside cells …

Cyclic cell-penetrating peptides as efficient intracellular drug delivery tools

SE Park, MI Sajid, K Parang, RK Tiwari - Molecular pharmaceutics, 2019 - ACS Publications
Cyclic cell-penetrating peptides are relatively a newer class of peptides that have a huge
potential for the intracellular delivery of therapeutic agents aimed at treating challenging …

[HTML][HTML] Protease-resistant peptides for targeting and intracellular delivery of therapeutics

MC Lucana, Y Arruga, E Petrachi, A Roig, R Lucchi… - Pharmaceutics, 2021 - mdpi.com
Peptides show high promise in the targeting and intracellular delivery of next-generation bio-
and nano-therapeutics. However, the proteolytic susceptibility of peptides is one of the major …

The recent advance of cell-penetrating and tumor-targeting peptides as drug delivery systems based on tumor microenvironment

Q Zhang, N Liu, J Wang, Y Liu, K Wang… - Molecular …, 2023 - ACS Publications
Cancer has become the primary reason for industrial countries death. Although first-line
treatments have achieved remarkable results in inhibiting tumors, they could have serious …

Trapped! A critical evaluation of methods for measuring total cellular uptake versus cytosolic localization

K Deprey, L Becker, J Kritzer… - Bioconjugate …, 2019 - ACS Publications
Biomolecules have many properties that make them promising for intracellular therapeutic
applications, but delivery remains a key challenge because large biomolecules cannot …

Leveraging the therapeutic, biological, and self-assembling potential of peptides for the treatment of viral infections

MK Monroe, H Wang, CF Anderson, H Jia… - Journal of Controlled …, 2022 - Elsevier
Peptides and peptide-based materials have an increasing role in the treatment of viral
infections through their use as active pharmaceutical ingredients, targeting moieties …

Tumor-derived extracellular vesicles in breast cancer: From bench to bedside

HX Wang, O Gires - Cancer letters, 2019 - Elsevier
Tumor-derived extracellular vesicles (TEVs) released from various tumor cell types comprise
endosome-derived exosomes and microvesicles (MVs), which originate from plasma …

[HTML][HTML] Peptide nanostructures-based delivery of DNA nanomaterial therapeutics for regulating gene expression

B Baral, B Panigrahi, A Kar, KD Tulsiyan… - … Therapy-Nucleic Acids, 2023 - cell.com
Self-assembled branched DNA (bDNA) nanomaterials have exhibited their functionality in
various biomedical and diagnostic applications. However, the anionic cellular membrane …