Ischemic stroke caused by arterial occlusion is the most common type of stroke, which is
among the most frequent causes of disability and death worldwide. Current treatment …

Perturbations in lipid homeostasis combined with conditions favoring oxidative stress
constitute a hallmark of the inflammatory response. In this review we focus on the most …

Phospholipids containing a single polyunsaturated fatty acyl tail (PL-PUFA 1 s) are
considered the driving force behind ferroptosis, whereas phospholipids with diacyl-PUFA …

Maintaining the high standards that made the previous editions such well-respected and
widely used references, Food Lipids: Chemistry, Nutrition, and Biotechnology, Fourth Edition …

Phospholipase A 2 s are enzymes that hydrolyze the fatty acid at the sn-2 position of the
glycerol backbone of membrane glycerophospholipids. Given the asymmetric distribution of …

Unlike other macronutrients such as protein, the amounts and types of fat in the human diet
vary tremendously across cultures and over time have changed significantly within …

The need for protein-mediated transport of long-chain fatty acids into the cell is hotly
debated, and the reviews make interesting reading (eg, refs. 4–9). One line of argument is …

Among the family of phospholipases A 2 (PLA 2 s) are the Ca 2+-independent PLA 2 s (iPLA
2 s) and they are designated group VI iPLA 2 s. In relation to secretory and cytosolic PLA 2 s …

Microglial cells are believed to play an active role in brain inflammatory, immune and
degenerative processes. Depending on the magnitude of microglial reaction, on the type of …

Arachidonic acid (AA) and its oxygenated derivatives, collectively known as the eicosanoids,
are key mediators of a wide variety of physiological and pathophysiological states. AA …