In female mammals, mechanisms have been developed, throughout evolution, to integrate
environmental, nutritional and hormonal cues in order to guarantee reproduction in …

Across the Western World there is an increasing trend to postpone childbearing.
Consequently, the negative influence of age on oocyte quality may lead to a difficulty in …

STUDY QUESTION Does an intensive weight reduction programme prior to IVF increase live
birth rates for infertile obese women? SUMMARY ANSWER An intensive weight reduction …

Background: Adequate dietary intake and nutritional status have important effects on brain
functions and on brain health. Energy intake and specific nutrients excess or deficiency from …

This review aimed to focus on the recent progress of the understanding of the role of
phosphatidylinositol 3-kinase (PI3K) in polycystic ovary syndrome (PCOS). In recent years, it …

Male fertility is declining in developed countries, as well as in developing countries. External
factors linked to lifestyle, such as eating disorders, negatively affect spermatogenesis, both …

In this review, we discuss the role of adipokines in the onset of puberty in children with
obesity during adrenarche and gonadarche and provide a clear and detailed overview of the …

Precocious puberty is defined as the appearance of secondary sex characteristics before 8
years of age in girls and before 9 years of age in boys. Central precocious puberty (CPP) is …

BACKGROUND Obesity and overweight are significantly involved in several reproductive
pathologies contributing to infertility in men and women. In addition, several cancers of the …

In recent decades, an increasing incidence of male infertility has been reported.
Interestingly, and considering that pesticides have been used for a long time, the high …