The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …

Microenvironment-responsive drug delivery systems (DDSs) can achieve targeted drug
delivery, reduce drug side effects and improve drug efficacies. Among them, pH-responsive …

Antibiotic-resistant bacterial infections arising from acquired resistance and/or through
biofilm formation necessitate the development of innovative 'outside of the box'therapeutics …

Highlights•The biofilm formation process and its microenvironmental characteristics are
described.•Biofilm microenvironment-responsive nanoparticles for anti-infection are …

The emergence and spread of antibiotic resistance is one of the biggest challenges in public
health. There is an urgent need to discover novel agents against the occurrence of multidrug …

In the past few decades, polymeric nanocarriers have been recognized as promising tools
and have gained attention from researchers for their potential to efficiently deliver bioactive …

The dramatic increase in antimicrobial resistance for pathogenic bacteria constitutes a key
threat to human health. The Centers for Disease Control and Prevention has recently stated …

Efficient antimicrobials are urgently needed for the treatment of bacterial biofilms due to their
resistance to traditional drugs. Photodynamic therapy (PDT) is a new strategy that has been …

Biofilm formation is a key virulence factor for a wide range of microorganisms that cause
chronic infections. The multifactorial nature of biofilm development and drug tolerance …

Pathogenic bacteria infection is a major public health problem due to the high morbidity and
mortality rates, as well as the increased expenditure on patient management. Although there …