Artificial intelligence for precision medicine in autoimmune liver disease

A Gerussi, M Scaravaglio, L Cristoferi, D Verda… - Frontiers in …, 2022 - frontiersin.org
Autoimmune liver diseases (AiLDs) are rare autoimmune conditions of the liver and the
biliary tree with unknown etiology and limited treatment options. AiLDs are inherently …

[HTML][HTML] Liver disease is a significant risk factor for cardiovascular outcomes–A UK Biobank study

A Roca-Fernandez, R Banerjee… - Journal of …, 2023 - Elsevier
Background & Aims Chronic liver disease (CLD) is associated with increased cardiovascular
disease (CVD) risk. We investigated whether early signs of liver disease (measured by iron …

Advanced MR imaging for detection of liver fibrosis and inflammation in autoimmune hepatitis: A state-of-the-art review

NBN Gomes, US Torres, MLCG Ferraz… - Seminars in Ultrasound …, 2024 - Elsevier
Autoimmune hepatitis (AIH) is a rare chronic liver disease, associated with a high level of
morbidity and high mortality; approximately 40% of patients with severe untreated disease …

Quantitative multiparametric MRI as a non-invasive stratification tool in children and adolescents with autoimmune liver disease

K Janowski, E Shumbayawonda, L Cheng… - Scientific Reports, 2021 - nature.com
Autoimmune hepatitis (AIH) and autoimmune sclerosing cholangitis (ASC) are two very
closely related autoimmune liver diseases with overlapping clinical features and similar …

Diagnostic accuracy of an uncorrected native T1 mapping sequence for liver fibrosis and inflammation in autoimmune hepatitis: A prospective study using …

NBN Gomes, US Torres, AHM Caiado, PS Fucuta… - La radiologia …, 2024 - Springer
Purpose There is an unmet clinical need for non-invasive imaging biomarkers that could
replace liver biopsy in the management of patients with autoimmune hepatitis (AIH). In this …

Liver magnetic resonance imaging, non-alcoholic fatty liver disease and metabolic syndrome risk in pre-pubertal Mexican boys

B de Celis Alonso, E Shumbayawonda, C Beyer… - Scientific Reports, 2024 - nature.com
Rising global pediatric obesity rates, increase non-alcoholic fatty liver disease (NAFLD) and
metabolic syndrome (MetS) prevalence, with MetS being a NAFLD risk factor. NAFLD can be …

Magnetic resonance elastography in evaluation of liver fibrosis in children with chronic liver disease

D Demirtaş, E Ünal, İS İdilman, Z Akçören… - Insights into …, 2023 - Springer
Background Magnetic resonance elastography (MRE) has been used to stage liver fibrosis
in adults. We aimed to assess the agreement between the Ishak scoring system and …

Fighting Amyotrophic Lateral Sclerosis by Protecting the Liver? A Prospective Cohort Study

L Zhu, Y Li, X Yu, Y Chen, J Zhang, C Pang… - Annals of …, 2024 - Wiley Online Library
Background Previous studies have observed liver abnormalities in amyotrophic lateral
sclerosis (ALS) patients. This study aimed to investigate whether early signs of liver disease …

Quantitative magnetic resonance imaging to aid clinical decision making in autoimmune hepatitis

MA Heneghan, E Shumbayawonda, A Dennis… - …, 2022 - thelancet.com
Background In autoimmune hepatitis (AIH), clinical practice and treatment guidelines
frequently diverge as a reflection of disease heterogeneity and challenges in achieving …

Associations between MRI T1 mapping, liver stiffness, quantitative MRCP, and laboratory biomarkers in children and young adults with autoimmune liver disease

N Mahalingam, AT Trout, DB Gandhi, RD Sahay… - Abdominal …, 2022 - Springer
Purpose Define relationships between quantitative magnetic resonance imaging (MRI)
metrics and clinical/laboratory data in a pediatric and young adult cohort with autoimmune …