Targeting inflammation in cancer prevention and therapy
Inflammation is associated with the development and malignant progression of most
cancers. As most of the cell types involved in cancer-associated inflammation are genetically …
cancers. As most of the cell types involved in cancer-associated inflammation are genetically …
Anti-inflammatory drugs and herbs with special emphasis on herbal medicines for countering inflammatory diseases and disorders-a review
Background: Diseases with inflammatory etiopathology have increased in incidence in
recent times. Drugs used for therapeutic management of such inflammatory diseases are …
recent times. Drugs used for therapeutic management of such inflammatory diseases are …
Microplastics induced inflammation and apoptosis via ferroptosis and the NF-κB pathway in carp
T Xu, J Cui, R Xu, J Cao, M Guo - Aquatic Toxicology, 2023 - Elsevier
Microplastics (MPs), a new class of pollutant that threatens aquatic biodiversity, are
becoming increasingly prevalent around the world. Fish growth may be severely inhibited by …
becoming increasingly prevalent around the world. Fish growth may be severely inhibited by …
Targeting the canonical WNT/β-catenin pathway in cancer treatment using non-steroidal anti-inflammatory drugs
A Vallée, Y Lecarpentier, JN Vallée - Cells, 2019 - mdpi.com
Chronic inflammation and oxidative stress are common and co-substantial pathological
processes accompanying and contributing to cancers. Numerous epidemiological studies …
processes accompanying and contributing to cancers. Numerous epidemiological studies …
Indomethacin-grafted and pH-sensitive dextran micelles for overcoming inflammation-mediated multidrug resistance in breast cancer
X Zeng, X Cheng, Y Zheng, G Yan, X Wang… - Carbohydrate …, 2020 - Elsevier
We first synthesized indomethacin (IND)-grafted dextran copolymer by acetal or ester
linkage, which self-assembled with doxorubicin (DOX) into prodrug micelles (ID AC/DOX or …
linkage, which self-assembled with doxorubicin (DOX) into prodrug micelles (ID AC/DOX or …
Synthesis of novel halogenated triarylpyrazoles as selective COX-2 inhibitors: anti-inflammatory activity, histopatholgical profile and in-silico studies
A novel series of halogenated triarylpyrazoles 12a-l was designed and synthesized. All
target compounds showed good in vitro COX-2 inhibitory activity (IC 50= 0.043–0.17 µM) …
target compounds showed good in vitro COX-2 inhibitory activity (IC 50= 0.043–0.17 µM) …
Novel applications of immuno-bioinformatics in vaccine and bio-product developments at research institutes
MM Ranjbar, MM Ebrahimi… - Archives of Razi …, 2019 - archrazi.areeo.ac.ir
There are many challenges in the field of public health sciences. Rational decisions are
required in order to treat different diseases, gain knowledge and wealth regarding research …
required in order to treat different diseases, gain knowledge and wealth regarding research …
Synthesis of acetaminophen‐based coumarins as selective COX‐2 inhibitors: An in vitro‐in silico study
MHM Jasim, YF Mustafa - Chemistry & Biodiversity, 2024 - Wiley Online Library
Acetaminophen, a centrally‐acting old analgesic drug, is a weak inhibitor of cyclooxygenase
(COX) isoforms with some selectivity toward COX‐2. This compound was used in this work …
(COX) isoforms with some selectivity toward COX‐2. This compound was used in this work …
The anti-inflammatory effects of Yunnan Baiyao are involved in regulation of the phospholipase A2/arachidonic acid metabolites pathways in acute inflammation rat …
X Ren, M Zhang, L Chen, W Zhang… - Molecular …, 2017 - spandidos-publications.com
Abstract The traditional Chinese medicine Yunnan Baiyao (YNB) has been reported to
possess anti‑inflammatory properties, however its mechanism of action remains unclear. It …
possess anti‑inflammatory properties, however its mechanism of action remains unclear. It …
Polygalactan from bivalve Crassostrea madrasensis attenuates nuclear factor-κB activation and cytokine production in lipopolysaccharide-activated macrophage
K Chakraborty, S Krishnan, M Joy - Carbohydrate Polymers, 2020 - Elsevier
A polygalactosamino-glucopyranosyl fucopyranose→ 4)-β-GlcAp {(3→ 1)-α-Fucp}-β-
GalNAcp-(4, 6-SO 3−)-(1→ isolated from the bivalve Crassostrea madrasensis exhibited …
GalNAcp-(4, 6-SO 3−)-(1→ isolated from the bivalve Crassostrea madrasensis exhibited …