Mesenchymal stem/stromal cells for rheumatoid arthritis treatment: an update on clinical applications
M Lopez-Santalla, R Fernandez-Perez, MI Garin - Cells, 2020 - mdpi.com
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects the lining of
the synovial joints leading to stiffness, pain, inflammation, loss of mobility, and erosion of …
the synovial joints leading to stiffness, pain, inflammation, loss of mobility, and erosion of …
Autophagy: a potential key contributor to the therapeutic action of mesenchymal stem cells
Macroautophagy/autophagy occurs at basal levels in all eukaryotic cells and plays an
important role in maintaining bio-energetic homeostasis through the control of molecule …
important role in maintaining bio-energetic homeostasis through the control of molecule …
The long path of human placenta, and its derivatives, in regenerative medicine
In the 1800s, a baby born with a caul, a remnant of the amniotic sack or fetal membranes,
was thought to be lucky, special, or protected. Over time, fetal membranes lost their …
was thought to be lucky, special, or protected. Over time, fetal membranes lost their …
Stem cell characteristics and the therapeutic potential of amniotic epithelial cells
T Miki - American Journal of Reproductive Immunology, 2018 - Wiley Online Library
Multiple stem cell types can be isolated from the human placenta. Recent advances in stem
cell biology have revealed that human amniotic epithelial cells (hAEC s) are one of the …
cell biology have revealed that human amniotic epithelial cells (hAEC s) are one of the …
Amniotic membrane-mesenchymal stromal cells secreted factors and extracellular vesicle-miRNAs: Anti-inflammatory and regenerative features for musculoskeletal …
E Ragni, A Papait, C Perucca Orfei… - Stem Cells …, 2021 - academic.oup.com
Human amniotic membrane-derived mesenchymal stromal cells (hAMSCs) are easily
obtained in large quantities and free from ethical concerns. Promising therapeutic results for …
obtained in large quantities and free from ethical concerns. Promising therapeutic results for …
The immunomodulatory properties of amniotic cells: the two sides of the coin
Among the many cell types useful in developing therapeutic treatments, human amniotic
cells from placenta have been proposed as valid candidates. Both human amniotic epithelial …
cells from placenta have been proposed as valid candidates. Both human amniotic epithelial …
Amniotic membrane mesenchymal cells-derived factors skew T cell polarization toward Treg and downregulate Th1 and Th17 cells subsets
S Pianta, P Bonassi Signoroni, I Muradore… - Stem Cell Reviews and …, 2015 - Springer
We previously demonstrated that cells derived from the mesenchymal layer of the human
amniotic membrane (hAMSC) and their conditioned medium (CM-hAMSC) modulate …
amniotic membrane (hAMSC) and their conditioned medium (CM-hAMSC) modulate …
Mesenchymal stromal cells from fetal and maternal placenta possess key similarities and differences: potential implications for their applications in regenerative …
A Papait, E Vertua, M Magatti, S Ceccariglia… - Cells, 2020 - mdpi.com
Placenta-derived mesenchymal stromal cells (MSC) have attracted more attention for their
immune modulatory properties and poor immunogenicity, which makes them suitable for …
immune modulatory properties and poor immunogenicity, which makes them suitable for …
Comparison of EV-free fraction, EVs, and total secretome of amniotic mesenchymal stromal cells for their immunomodulatory potential: A translational perspective
A Papait, E Ragni, A Cargnoni, E Vertua… - Frontiers in …, 2022 - frontiersin.org
Amniotic mesenchymal stromal cells (hAMSCs) have unique immunomodulatory properties
demonstrated in vitro and in vivo in various diseases in which the dysregulated immune …
demonstrated in vitro and in vivo in various diseases in which the dysregulated immune …
Mesenchymal stem/stromal cell-based therapy for the treatment of rheumatoid arthritis: An update on preclinical studies
M Lopez-Santalla, JA Bueren, MI Garin - EBioMedicine, 2021 - thelancet.com
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by
synovial inflammation and progressive joint destruction and is a primary cause of disability …
synovial inflammation and progressive joint destruction and is a primary cause of disability …