Recent advances in preclinical modeling of urinary tract infections (UTIs) have enabled the
identification of key facets of the host response that influence pathogen clearance and tissue …

Bladder cancer is a prevalent but currently understudied cancer type and patient outcomes
are poor when it progresses to the muscle-invasive stage. Current research in bladder …

Two resident macrophage subsets reside in peritoneal fluid. Macrophages also reside within
mesothelial membranes lining the peritoneal cavity, but they remain poorly characterized …

The salivary glands often become damaged in individuals receiving radiotherapy for head
and neck cancer, resulting in chronic dry mouth. This leads to detrimental effects on their …

It is often difficult to regain neurological function following spinal cord injury (SCI).
Neuroinflammation is thought to be responsible for this failure. Regulating the inflammatory …

Phagocytosis is a dynamic process that requires an intricate interplay between phagocytic
receptors, membrane lipids, and numerous signalling proteins and their effectors, to …

Interstitial cystitis/bladder pain syndrome (IC/BPS) has a significant impact on quality of life,
but the etiopathogenesis remains largely unknown. The bladder microenvironment of …

Abstract Treatment for higher‐risk non‐muscle invasive bladder cancer (NMIBC) involves
intravesical immunotherapy with Bacillus Calmette Guérin (BCG); however, disease …

An intricate relationship between impaired immune functions and the age-related
accumulation of tissue senescent cells is rapidly emerging. The immune system is unique as …

Circulating Ly6Chi monocytes often undergo cellular death upon exhaustion of their
antibacterial effector functions, which limits their capacity for subsequent macrophage …