[HTML][HTML] Neurobiology and consequences of social isolation stress in animal model—A comprehensive review

F Mumtaz, MI Khan, M Zubair, AR Dehpour - Biomedicine & …, 2018 - Elsevier
The brain is a vital organ, susceptible to alterations under genetic influences and
environmental experiences. Social isolation (SI) acts as a stressor which results in …

Endogenous opiates and behavior: 2015

RJ Bodnar - Peptides, 2017 - Elsevier
This paper is the thirty-eighth consecutive installment of the annual review of research
concerning the endogenous opioid system. It summarizes papers published during 2015 …

Possible interaction of opioidergic and nitrergic pathways in the anticonvulsant effect of ivermectin on pentylenetetrazole-induced clonic seizures in mice

S Jourian, M Rahimi, MA Manavi… - Neurochemical …, 2023 - Springer
Ivermectin (IVM) is an antiparasitic drug that primarily works by the activation of GABAA
receptors. The potential pharmacological pathways behind the anti-convulsant effect of IVM …

Fluoxetine reverses the behavioral despair induced by neurogenic stress in mice: role of N-methyl-d-aspartate and opioid receptors

A Haj-Mirzaian, N Kordjazy, S Ostadhadi… - Canadian journal of …, 2016 - cdnsciencepub.com
Opioid and N-methyl-d-aspartate (NMDA) receptors mediate different effects of fluoxetine.
We investigated whether opioid and NMDA receptors are involved in the protective effect of …

Experiencing neonatal maternal separation increased the seizure threshold in adult male mice: involvement of the opioid system

H Amini-Khoei, S Amiri, A Shirzadian, A Haj-Mirzaian… - Epilepsy & Behavior, 2015 - Elsevier
Experiencing early-life stress has been considered as a potent risk factor for the
development of many of brain disorders, including seizures. Intervening mechanisms …

NMDA receptor antagonists attenuate the proconvulsant effect of juvenile social isolation in male mice

S Amiri, A Haj-Mirzaian, H Amini-khoei, M Momeny… - Brain Research …, 2016 - Elsevier
Experiencing psychosocial stress in early life, such as social isolation stress (SIS), is known
to have negative enduring effects on the development of the brain and behavior. In addition …

Morphine modulates the effects of histamine H1 and H3 receptors on seizure susceptibility in pentylenetetrazole-induced seizure model of mice

H Amini-Khoei, M Rahimi-Balaei, S Amiri… - European Journal of …, 2015 - Elsevier
Histamine regulates release of neurotransmitters such as dopamine, serotonin, gamma-
aminobutyric acid (GABA), glutamate and also is involved in several functions in central …

[HTML][HTML] The possible role of nitric oxide in anti-convulsant effects of Naltrindole in seizure-induced by social isolation stress in male mice

R Nikbakhsh, R Nikbakhsh, M Radmard… - Biomedicine & …, 2020 - Elsevier
Social isolation stress (SIS) as a chronic model of early-life stress could induce
proconvulsant effects in mice. In the current study, we evaluated the role of opioid receptors …

The potential role of very small embryonic-like stem cells in the neuroinflammation induced by social isolation stress: Introduction of a new paradigm

A Haj-Mirzaian, A Khosravi, A Haj-Mirzaian… - Brain Research …, 2020 - Elsevier
Lack of social contacts could induce psychiatric features and lead to various behavioral and
neurochemical abnormalities in rodents. Social isolation stress (SIS) is a valid paradigm of …

Acute foot-shock stress decreased seizure susceptibility against pentylenetetrazole-induced seizures in mice: Interaction between endogenous opioids and …

A Shirzadian, S Ostadhadi, M Hassanipour… - Epilepsy & Behavior, 2018 - Elsevier
Background Stressful conditions affect the brain's neurotransmission and neural pathways
that are involved in seizure susceptibility. Stress alters the intensity and/or frequency of …