A journey through 50 years of research relevant to the control of gastrointestinal nematodes in ruminant livestock and thoughts on future directions

JS Gilleard, AC Kotze, D Leathwick, AJ Nisbet… - International Journal for …, 2021 - Elsevier
This review article provides an historical perspective on some of the major research
advances of relevance to ruminant livestock gastrointestinal nematode control over the last …

The immunobiology of gastrointestinal nematode infections in ruminants

A Balic, VM Bowles, ENT Meeusen - 2000 - Elsevier
The major gastrointestinal nematode parasites of ruminants all belong to the Order
Strongylida and the family Trichostrongyloidea. Despite this close evolutionary relationship …

Haemonchosis in Sheep and Goats, Control Strategies and Development of Vaccines against Haemonchus contortus

I Adduci, F Sajovitz, B Hinney, K Lichtmannsperger… - Animals, 2022 - mdpi.com
Simple Summary Haemonchus contortus is the most pathogenic blood-feeding parasitic
nematode in sheep and goats, threatening animal welfare and causing tremendous …

Relationship of abomasal histology and parasite-specific immunoglobulin A with the resistance to Haemonchus contortus infection in three breeds of sheep

AFT Amarante, PA Bricarello, JF Huntley… - Veterinary …, 2005 - Elsevier
This study was carried out to evaluate the relationship of abomasal inflammatory cells and
parasite-specific immunoglobulin A (IgA) in mucus, with the resistance to Haemonchus …

Cellular profiles in the abomasal mucosa and lymph node during primary infection with Haemonchus contortus in sheep

A Balic, VM Bowles, ENT Meeusen - Veterinary immunology and …, 2000 - Elsevier
Cellular changes in the abomasal tissue and draining abomasal lymph nodes were
examined after primary infection of lambs with Haemonchus contortus for 3, 5 or 27–36 …

[HTML][HTML] Core α1→ 3-fucose is a common modification of N-glycans in parasitic helminths and constitutes an important epitope for IgE from Haemonchus contortus …

I van Die, V Gomord, FNJ Kooyman, TK van den Berg… - FEBS letters, 1999 - Elsevier
Synthesis of parasite specific IgE plays a critical role in the defence against helminth
infections. We report here that IgE from serum from Schistosoma mansoni infected mice and …

Immunoglobulins as biomarkers for gastrointestinal nematodes resistance in small ruminants: A systematic review

HM Aboshady, MJ Stear, A Johansson, E Jonas… - Scientific reports, 2020 - nature.com
The rise of anthelmintic resistance worldwide has led to the development of alternative
control strategies for gastrointestinal nematodes (GIN) infections, which are one of the main …

A Th2 type of immune response is associated with increased resistance to Haemonchus contortus in naturally infected Gulf Coast Native lambs

KP Shakya, JE Miller, DW Horohov - Veterinary Parasitology, 2009 - Elsevier
Haemonchus contortus is one of the major nematode parasites causing substantial
economic losses in small ruminant farming worldwide. Recently, effectiveness of …

Vaccination against the nematode Haemonchus contortus with a thiol-binding fraction from the excretory/secretory products (ES)

N Bakker, L Vervelde, K Kanobana, DP Knox… - Vaccine, 2004 - Elsevier
Fractionated excretory/secretory products (ES) of adult Haemonchus contortus were
evaluated as protective antigens. The proteins were successively eluted from a Thiol …

Genetic analysis of the potential role of IgA and IgE responses against Haemonchus contortus in parasite resistance of Creole goats

C de La Chevrotiere, JC Bambou, R Arquet… - Veterinary …, 2012 - Elsevier
Small ruminants are affected by gastrointestinal nematode (GIN) infection. A promising
alternative strategy for control of GIN infection is to increase the level of resistance in the …