The growing disease burden of diabetes mellitus is an important public health concern,
affecting over 400 million people globally. This epidemic, if not controlled in time, leads to …

Alcohol-related diseases of the nervous system are caused by excessive exposures to
alcohol, with or without co-existing nutritional or vitamin deficiencies. Toxic and metabolic …

Growing evidence supports the concept that Alzheimer's disease (AD) is fundamentally a
metabolic disease with molecular and biochemical features that correspond with diabetes …

Alzheimer's disease [AD] is the most common cause of dementia in North America. Despite
30+ years of intense investigation, the field lacks consensus regarding the etiology and …

This article summarizes recent experimental and epidemiological data on the toxic and
beneficial effects of ethanol and its metabolites (acetaldehyde), and focuses on their …

Ceramide has been suggested to participate in the neuronal cell death that leads to
Alzheimer's disease (AD), but its role is not yet well-understood. We compared the levels of …

Recent evidence indicates that Parkinson's disease and diabetes, both age-related chronic
diseases, share remarkably similar dysregulated pathways. Exposure to environmental …

The excessive intake of alcohol is a serious public health problem, especially given the
severe damage provoked by chronic or prenatal exposure to alcohol that affects many …

The blood brain barrier (BBB) is a highly dynamic interface between the central nervous
system (CNS) and periphery. The BBB is comprised of a number of components and is part …

Cognitive processes, particularly learning and memory, are crucial brain mechanisms
mediating the successful adaptation of individuals to constantly changing environmental …