Triple negative breast cancer: a review of present and future diagnostic modalities

SA Dass, KL Tan, R Selva Rajan, NF Mokhtar… - Medicina, 2021 - mdpi.com
Triple-negative breast cancer (TNBC) is an aggressive breast type of cancer with no
expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal …

[HTML][HTML] Significance of immunohistochemistry in breast cancer

DC Zaha - World journal of clinical oncology, 2014 - ncbi.nlm.nih.gov
The biological characteristics of the tumour are used to estimate prognosis and select
appropriate systemic therapy for patients with (breast) cancer. The advent of molecular …

Ki-67 is a prognostic parameter in breast cancer patients: results of a large population-based cohort of a cancer registry

EC Inwald, M Klinkhammer-Schalke… - Breast cancer research …, 2013 - Springer
The proliferation marker Ki-67 is one of the most controversially discussed parameters for
treatment decisions in breast cancer patients. The purpose of this study was to evaluate the …

The prognostic and predictive potential of Ki-67 in triple-negative breast cancer

X Zhu, L Chen, B Huang, Y Wang, L Ji, J Wu, G Di… - Scientific reports, 2020 - nature.com
As a cell proliferation biomarker, Ki-67 is principally used in ER+/HER2− breast cancer.
However, the importance and the best cutoff point of Ki-67 in triple-negative breast cancer …

CD44+/CD24−/low cancer stem/progenitor cells are more abundant in triple-negative invasive breast carcinoma phenotype and are associated with poor outcome

MO Idowu, M Kmieciak, C Dumur, RS Burton… - Human pathology, 2012 - Elsevier
Women classified as having triple-negative tumors have a poor prognosis. The importance
of CD44+/CD24−/low (stem/progenitor cell-phenotype) in breast cancer patients has also …

Retrospective analysis of metastatic behaviour of breast cancer subtypes

CD Savci-Heijink, H Halfwerk, GKJ Hooijer… - Breast cancer research …, 2015 - Springer
Among breast cancer patients who develop distant metastases, there is marked variability in
the clinical course, including metastasis pattern. Here, we present a retrospective study of …

Hyperthermia can alter tumor physiology and improve chemo-and radio-therapy efficacy

M Dunne, M Regenold, C Allen - Advanced Drug Delivery Reviews, 2020 - Elsevier
Hyperthermia has demonstrated clinical success in improving the efficacy of both chemo-
and radio-therapy in solid tumors. Pre-clinical and clinical research studies have …

[HTML][HTML] Biomarkers in triple negative breast cancer: A review

BS Yadav, P Chanana, S Jhamb - World journal of clinical oncology, 2015 - ncbi.nlm.nih.gov
Breast cancer is an intrinsically heterogeneous disease. In the world about 1 million cases of
breast cancer are diagnosed annually and more than 170000 are triple-negative …

Triple-negative breast carcinoma: current and emerging concepts

R Schmadeka, BE Harmon… - American journal of clinical …, 2014 - academic.oup.com
Objectives: Triple-negative breast cancer is regarded as an aggressive disease that affects a
young patient population and for which effective targeted therapy is not yet available …

Update on triple-negative breast cancer: prognosis and management strategies

O Brouckaert, H Wildiers, G Floris… - International journal of …, 2012 - Taylor & Francis
Triple negative breast cancer (TNBC) is a heterogeneous disease comprehending different
orphan breast cancers simply defined by the absence of ER/PR/HER-2. Approximately 15 …