The integrated stress response (ISR) is a highly conserved biochemical pathway that
regulates protein synthesis. The ISR is activated in response to diverse stressors to restore …

Introduction: Alzheimer's disease (AD) is an intensifying neurodegenerative illness due to its
irreversible nature. Identification of β128; site Amyloid Precursor Protein (APP) cleaving en …

Alzheimer's disease (AD) is tightly related to endoplasmic reticulum stress (ER stress), which
aggravates two dominant pathological manifestations of AD: senile plaques and …

Exploring the potential lead compounds for Alzheimer's disease (AD) remains one of the
challenging tasks. Here, we report that the plant extract conophylline (CNP) impeded …

Neurodegenerative and inflammatory processes influence the clinical course of multiple
sclerosis (MS). The β-site amyloid precursor protein cleaving enzyme 1 (BACE1) has been …

Alzheimer's disease (AD) is a chronic neurological condition that has become a leading
cause of cognitive decline in elder individuals. Hardly any effective medication has been …

Repeated cocaine use poses many serious health risks to users. One of the risks is hypoxia
and ischemia (HI). To restore the biological system against HI, complex biological …

Numerous environmental risk factors are now recognised as contributors to the onset and
progression of Alzheimer's disease (AD). It is probable that, in most instances, AD arises …

Alzheimer's Disease (AD) is a devastating neurodegenerative disorder affecting all tissues
and cell types of brain leading to emotional dysregulation and cognitive dysfunction. From …

Alzheimer's disease (AD) and Parkinson's disease (PD) are neurodegenerative diseases
that are caused by brain degeneration and lead to severe memory decline. According to the …