[HTML][HTML] Thiol functionalised gold nanoparticles loaded with methotrexate for cancer treatment: From synthesis to in vitro studies on neuroblastoma cell lines

TA Salamone, L Rutigliano, B Pennacchi… - Journal of Colloid and …, 2023 - Elsevier
Abstract Hypothesis Colloidal gold nanoparticles (AuNPs) functionalised with hydrophilic
thiols can be used as drug delivery probes, thanks to their small size and hydrophilic …

Albumin–Methotrexate Prodrug Analogues That Undergo Intracellular Reactivation Following Entrance into Cancerous Glioma Cells

I Cooper, M Schnaider-Beeri, M Fridkin, Y Shechter - Pharmaceutics, 2021 - mdpi.com
A family of monomodified bovine serum albumin (BSA) linked to methotrexate (MTX) through
a variety of spacers was prepared. All analogues were found to be prodrugs having low MTX …

Albumin-EDTA-vanadium is a powerful anti-proliferative agent, following entrance into glioma cells via caveolae-mediated endocytosis

I Cooper, O Ravid, D Rand, D Atrakchi, C Shemesh… - Pharmaceutics, 2021 - mdpi.com
Human serum albumin (HSA) is efficiently taken up by cancer cells as a source of carbon
and energy. In this study, we prepared a monomodified derivative of HSA covalently linked …

Bicyclic 6-6 systems: pteridines

S Rossiter, M Ostovar - Comprehensive Heterocyclic Chemistry IV, 2022 - uhra.herts.ac.uk
This article describes the literature on pteridines, covering the period from 2008 to 2020. The
physical properties and reactions include photochemistry, substitution at ring nitrogens …