Depression and anxiety in inflammatory bowel disease: epidemiology, mechanisms and treatment

TH Bisgaard, KH Allin, L Keefer… - Nature reviews …, 2022 - nature.com
Inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis, is a
chronic, relapsing immune-mediated disease with a varying and sometimes severe disease …

British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults

CA Lamb, NA Kennedy, T Raine, PA Hendy, PJ Smith… - Gut, 2019 - gut.bmj.com
Ulcerative colitis and Crohn's disease are the principal forms of inflammatory bowel disease.
Both represent chronic inflammation of the gastrointestinal tract, which displays …

Tryptophan-kynurenine metabolism: a link between the gut and brain for depression in inflammatory bowel disease

LM Chen, CH Bao, Y Wu, SH Liang, D Wang… - Journal of …, 2021 - Springer
Inflammatory bowel disease (IBD), which mainly includes ulcerative colitis (UC) and Crohn's
disease (CD), is a group of chronic bowel diseases that are characterized by abdominal …

[HTML][HTML] Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders

JR Kelly, PJ Kennedy, JF Cryan, TG Dinan… - Frontiers in cellular …, 2015 - frontiersin.org
The emerging links between our gut microbiome and the central nervous system are
regarded as a paradigm shift in neuroscience with possible implications for not only …

Depression and anxiety in patients with inflammatory bowel disease: a systematic review

R Neuendorf, A Harding, N Stello, D Hanes… - Journal of …, 2016 - Elsevier
Objective An increasing number of studies have been conducted to look at anxiety and
depression in IBD; however, there is no clear consensus on the prevalence of anxiety and …

Controversies revisited: a systematic review of the comorbidity of depression and anxiety with inflammatory bowel diseases

A Mikocka-Walus, SR Knowles… - Inflammatory bowel …, 2016 - academic.oup.com
Background Although mental health concerns are known to occur commonly for those with
inflammatory bowel diseases (IBD), the nature of this comorbid relationship has not been …

The intestinal microbiota affect central levels of brain-derived neurotropic factor and behavior in mice

P Bercik, E Denou, J Collins, W Jackson, J Lu, J Jury… - Gastroenterology, 2011 - Elsevier
BACKGROUND & AIMS: Alterations in the microbial composition of the gastrointestinal tract
(dysbiosis) are believed to contribute to inflammatory and functional bowel disorders and …

Environmental risk factors for inflammatory bowel disease

N Singh, CN Bernstein - United European gastroenterology …, 2022 - Wiley Online Library
Inflammatory bowel disease (IBD) is a chronic, progressive immunemediated inflammatory
condition of the gastrointestinal tract. Environmental risk factors play a role in developing …

The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut–brain communication

P Bercik, AJ Park, D Sinclair, A Khoshdel… - …, 2011 - Wiley Online Library
Abstract Background The probiotic Bifidobacterium longum NCC3001 normalizes anxiety
like behavior and hippocampal brain derived neurotrophic factor (BDNF) in mice with …

Guidelines for the management of inflammatory bowel disease in adults

C Mowat, A Cole, AL Windsor, T Ahmad, I Arnott… - Gut, 2011 - gut.bmj.com
The management of inflammatory bowel disease represents a key component of clinical
practice for members of the British Society of Gastroenterology (BSG). There has been …