Lignocellulosic biomass is the most abundant sustainable carbon source on the planet and
has enormous potential to substitute fossil resources on the premise of cost-effective …

The Clostridium genus is a large, diverse group consisting of Gram-positive, spore-forming,
obligate anaerobic firmicutes. Among this group are historically notorious pathogens as well …

Clostridium butyricum has been widely used as a probiotic for humans and food animals.
However, the mechanisms of beneficial effects of C. butyricum on the host remain poorly …

Highlights•There exists an expanding list of inducible systems in non-model
organisms.•Current engineering methods are often species-specific.•High-throughput …

Intestinal probiotics are often used for the in situ treatment of diseases, such as metabolic
disorders, tumors, and chronic inflammatory infections. Recently, there has been an …

Cost-efficient production of pullulan is of great importance but remains challenging due
largely to the high-cost carbon sources. Lignocellulosic biomass is considered an alternative …

The advantage of using acetogens such as Acetobacterium woodii as biocatalysts
converting the cheap substrate and greenhouse gas carbon dioxide (CO 2) into value …

Background The industrial conversion of biomass to high-value biofuels and biochemical is
mainly restricted by lignocellulose solubilization. Consolidated bio-saccharification (CBS) is …

Background Cost-efficient saccharification is one of the main bottlenecks for industrial
lignocellulose conversion. Clostridium thermocellum naturally degrades lignocellulose …

CRISPR-Cpf1 is a type V CRISPR system that has recently been exploited for genome
engineering purposes. Compared to the well-known Streptococcus pyogenes CRISPR …