Given that cancer mortality is usually a result of late diagnosis, efforts in the field of early
detection are paramount to reducing cancer-related deaths and improving patient outcomes …

Carcinogenesis is accompanied by widespread DNA methylation changes within the cell.
These changes are characterized by a globally hypomethylated genome with focal …

Liquid biopsies, in particular, analysis of cell-free DNA (cfDNA), have emerged as a
promising noninvasive diagnostic approach in oncology. Abnormal distribution of DNA …

Liquid biopsies (LBs), particularly using circulating tumor DNA (ctDNA), are expected to
revolutionize precision oncology and blood-based cancer screening. Recent technological …

Advances in biomarkers, targeted therapies, and immuno-oncology have transformed the
clinical management of patients with advanced NSCLC. For oncogene-driven tumors, there …

BACKGROUND Current methods for the detection and surveillance of bladder cancer (BCa)
are often invasive and/or possess suboptimal sensitivity and specificity, especially in early …

Lung cancer (LC) is the main cause of cancer-related mortality. Most LC patients are
diagnosed in an advanced stage when the symptoms are obvious, and the prognosis is …

Background Liquid biopsy has been widely researched for early diagnosis, prognostication
and disease monitoring in lung cancer, but there is a need to investigate its clinical utility for …

Background There is an unmet clinical need for accurate non-invasive tests to facilitate the
early diagnosis of lung cancer. We propose a combined model of clinical, imaging, and cell …

The increase in recent scientific studies on cancer biomarkers has brought great new
insights into the field. Moreover, novel technological breakthroughs such as long read …