Modelling glioblastoma resistance to temozolomide. A mathematical model to simulate cellular adaptation in vitro
M Pérez-Aliacar, J Ayensa-Jiménez… - Computers in Biology …, 2024 - Elsevier
Drug resistance is one of the biggest challenges in the fight against cancer. In particular, in
the case of glioblastoma, the most lethal brain tumour, resistance to temozolomide (the …
the case of glioblastoma, the most lethal brain tumour, resistance to temozolomide (the …
Characterising cancer cell responses to cyclic hypoxia using mathematical modelling
In vivo observations show that oxygen levels in tumours can fluctuate on fast and slow
timescales. As a result, cancer cells can be periodically exposed to pathologically low …
timescales. As a result, cancer cells can be periodically exposed to pathologically low …
Modelling glioblastoma resistance to temozolomide. Combination of spheroid and mathematical models to simulate cellular adaptation in vitro
Drug resistance is one of the biggest challenges in the fight against cancer. In particular, in
the case of glioblastoma, the most lethal brain tumour, resistance to temozolomide (the …
the case of glioblastoma, the most lethal brain tumour, resistance to temozolomide (the …
Design of Treatments for Overcoming Drug Resistance in Glioblastoma Cultures with a Mathematical Model of Cellular Adaptation
M Pérez-Aliacar, J Ayensa-Jiménez… - … Symposium on Computer …, 2023 - Springer
Drug resistance is one of the main limiting factors for the success of existing cancer
therapies and the development of new ones. In particular, for glioblastoma, the most …
therapies and the development of new ones. In particular, for glioblastoma, the most …