Metabolic reprogramming is one of the main characteristics of malignant tumors, which is
due to the flexible changes of cell metabolism that can meet the needs of cell growth and …

Altered metabolism is a hallmark of cancer, and the reprogramming of energy metabolism
has historically been considered a general phenomenon of tumors. It is well recognized that …

Metabolic reprogramming, including enhanced biosynthesis of macromolecules, altered
energy metabolism, and maintenance of redox homeostasis, is considered a hallmark of …

Objective Microbiota disorder promotes chronic inflammation and carcinogenesis. High
glycolysis is associated with poor prognosis in patients with colorectal cancer (CRC) …

Reversible, spatial, and temporal regulation of metabolic reprogramming and epigenetic
homeostasis are prominent hallmarks of carcinogenesis. Cancer cells reprogram their …

Abstract Background Long non-coding RNAs (lncRNAs) are important epigenetic regulators,
which play critical roles in diverse physiological and pathological processes. However, the …

Aromatase inhibition is an efficient endocrine therapy to block ectopic estrogen production
for postmenopausal estrogen receptor (ER)-positive breast cancer patients, but many …

Long non-coding RNAs (lncRNAs) play critical roles in tumorigenesis and progression of
colorectal cancer (CRC). However, functions of most lncRNAs in CRC and their molecular …

Background NCAPD3 is one of the three non-SMC subunits of condensin II complex, which
plays an important role in the chromosome condensation and segregation during mitosis …

Abstract Acylphosphatase 1 (ACYP1), a protein located in the mammalian cell cytoplasm,
has been shown to be associated with tumor initiation and progression by functioning as a …