Cancer is one of the major causes of death and a significant obstacle to increasing life
expectancy worldwide. Chemotherapy remains the first-line adjuvant therapeutic option for …

Primary liver cancer is the sixth most common cancer and the third most common cause of
cancer-related deaths worldwide. Hepatocellular carcinoma (HCC) is a major histologic type …

Abstract RAS/RAF/MEK/ERK signaling pathway is one of the most important pathways of
Mitogen-activated protein kinases (MAPK), which widely participate in regulating cell …

Despite pharmacological advances such as lenvatinib approval, therapeutic failure of
hepatocellular carcinoma (HCC) remains a big challenge due to the complexity of its …

The pathogenesis of hepatocellular carcinoma (HCC) is a multifactorial process that has not
yet been fully investigated. Autophagy and apoptosis are two important cellular pathways …

Abstract Background and Aims Lenvatinib is a first‐line drug commonly used in the
treatment of advanced hepatocellular carcinoma (HCC). However, its clinical efficacy is very …

Objective: Keloids are benign fibroproliferative disorders with invasive growth exceeding the
wound boundary. Aurora kinase A (AURKA) is a serine/threonine kinase highly expressed in …

Background Aging is a multifactorial degenerative process that can be modulated by fasting
through activation of the Fork-head transcription factor of the O class 3 (FOXO3), which plays …