Cells live in a chemical environment and are able to orient towards chemical cues.
Unicellular haploid fungal cells communicate by secreting pheromones to reproduce …

Fungi exhibit an enormous variety of morphologies, including yeast colonies, hyphal
mycelia, and elaborate fruiting bodies. This diversity arises through a combination of polar …

Since its identification, Saccharomyces eubayanus has been recognized as the missing
parent of the lager hybrid, S. pastorianus. This wild yeast has never been isolated from …

Gene expression noise arises from stochastic variation in the synthesis and degradation of
mRNA and protein molecules and creates differences in protein numbers across …

Communication by means of diffusible signaling molecules facilitates higher-level
organization of cellular populations. Gram-positive bacteria frequently use signaling …

Studies of laboratory strains of Saccharomyces cerevisiae have uncovered signaling
pathways involved in mating, including information-processing strategies to optimize …

Gene regulatory networks are largely responsible for cellular decision-making. These
networks sense diverse external signals and respond by adjusting gene expression …

Cellular processes are inherently noisy, and the selection for accurate responses in
presence of noise has likely shaped signalling networks. Here, we investigate the trade-off …

Most ascomycete fungi, including the fission yeast Schizosaccharomyces pombe, secrete
two peptidyl mating pheromones: C-terminally modified and unmodified peptides. S. pombe …

Synthetic biology is revolutionizing our approaches to biocomputing, diagnostics, and
environmental monitoring through the use of designed genetic circuits that perform a …