Mitochondria are the source of cellular energy production and are present in different types
of cells. However, their function is especially important for the heart due to the high demands …

Perivascular adipose tissue (PVAT) is an additional special type of adipose tissue
surrounding blood vessels. Under physiological conditions, PVAT plays a significant role in …

Reactive oxygen and nitrogen species are produced in a wide range of physiological
reactions that, at low concentrations, play essential roles in living organisms. There is a …

Adipose tissues are present at multiple locations in the body. Most blood vessels are
surrounded with adipose tissue which is referred to as perivascular adipose tissue (PVAT) …

Excess visceral adiposity, in particular that located adjacent to the heart and coronary
arteries is associated with increased cardiovascular risk. In the pathophysiological state …

Perivascular adipose tissue (PVAT) refers to the aggregate of adipose tissue surrounding
the vasculature, exhibiting the phenotypes of white, beige and brown adipocytes. PVAT has …

Cardiovascular diseases (CVDs) rank the leading cause of morbidity and mortality globally.
Obesity and its related metabolic syndrome are well-established risk factors for CVDs …

Obesity is associated with increased risk of premature death, morbidity, and mortality from
several cardiovascular diseases (CVDs), including stroke, coronary heart disease (CHD) …

Perivascular adipose tissue (PVAT) is a specialized type of adipose tissue that surrounds
most mammalian blood vessels. PVAT is a metabolically active, endocrine organ capable of …

Perivascular adipose tissue (PVAT) is a special type of ectopic fat depot that adheres to most
vasculatures. PVAT has been shown to exert anticontractile effects on the blood vessels and …