Fibril-Guided Three-Dimensional Assembly of Human Fibroblastic Reticular Cells

KY Velankar, W Liu, PR Hartmeier… - ACS Applied Bio …, 2024 - ACS Publications
Fibroblastic reticular cells (FRCs) are stromal cells (SCs) that can be isolated from lymph
node (LN) biopsies. Studies have shown that these nonhematopoietic cells have the …

A comprehensive multi-omics signature of doxorubicin-induced cellular senescence in the postmenopausal human ovary.

PR Devrukhkar, M Watson, B Soygur, F Wu, J Bons… - bioRxiv, 2024 - biorxiv.org
A major aging hallmark is the accumulation of cellular senescence burden. Over time
senescent cells contribute to tissue deterioration through chronic inflammation and fibrosis …

Rapamycin Immunomodulation Utilizes Time-Dependent Alterations of Lymph Node Architecture, Leukocyte Trafficking, and Gut Microbiome

L Wu, A Kensiski, S Gavzy, HW Lwin, Y Song, M France… - bioRxiv, 2024 - biorxiv.org
Transplant recipients require lifelong, multimodal immunosuppression to prevent rejection
by reducing alloreactive immunity. Rapamycin, a mechanistic target of rapamycin (mTOR) …

Viral Infection Induces Subset-and Age-specific Gene Expression Patterns in Lymph Node Stromal Cells

A Bennett - 2024 - search.proquest.com
West Nile virus (WNV), a flavivirus endemic to the United States, typically causes
asymptomatic infection. However, the probability of severe WNV neurological disease …